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Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results.

Publication ,  Journal Article
Marin, D; Soher, BJ; Dale, BM; Boll, DT; Youngblood, RS; Merkle, EM
Published in: Radiology
January 2010

PURPOSE: To retrospectively compare a two-dimensional (2D) and a three-dimensional (3D) technique for in-phase (IP) and opposed-phase (OP) single-breath-hold 3-T magnetic resonance (MR) imaging in the characterization of adrenal lesions, with histopathologic confirmation, computed tomographic findings, or imaging follow-up for a minimum of 6 months used as the reference standard. MATERIALS AND METHODS: This retrospective HIPAA-compliant study was approved by institutional review board, and a waiver of informed consent was obtained. Thirty-four patients (mean age, 57 years) with 37 adrenal lesions underwent 3-T adrenal MR imaging with both 2D and 3D single-breath-hold dual gradient-echo (GRE) MR sequences. Signal intensity (SI) index and adrenal-to-spleen, adrenal-to-liver, and adrenal-to-muscle SI ratios for each lesion were compared between the two techniques by using repeated-measures analysis of variance. The area under the receiver operating characteristic curve (AUC) for each evaluation method was determined, with retrospective selection of suggested thresholds. RESULTS: For the 2D and 3D techniques, the mean SI index and SI ratios were significantly different between adenomas and nonadenomas (P < .05), except for the adrenal-to-liver SI ratio with the 2D technique and the adrenal-to-muscle SI ratio with both techniques. For all evaluation methods, the AUCs were higher, although not statistically significant, for the 3D technique. The two techniques exploited different suggested thresholds for discriminating adenomas from nonadenomas. CONCLUSION: Adrenal adenomas can be readily differentiated from nonadenomas at 3-T MR imaging with either a 2D or 3D single-breath-hold dual GRE MR technique. Depending on the acquisition technique, different suggested thresholds need to be selected for various evaluation methods.

Duke Scholars

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

January 2010

Volume

254

Issue

1

Start / End Page

179 / 187

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Reference Standards
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Imaging, Three-Dimensional
  • Image Interpretation, Computer-Assisted
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Marin, D., Soher, B. J., Dale, B. M., Boll, D. T., Youngblood, R. S., & Merkle, E. M. (2010). Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results. Radiology, 254(1), 179–187. https://doi.org/10.1148/radiol.09090486
Marin, Daniele, Brian J. Soher, Brian M. Dale, Daniel T. Boll, Richard S. Youngblood, and Elmar M. Merkle. “Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results.Radiology 254, no. 1 (January 2010): 179–87. https://doi.org/10.1148/radiol.09090486.
Marin D, Soher BJ, Dale BM, Boll DT, Youngblood RS, Merkle EM. Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results. Radiology. 2010 Jan;254(1):179–87.
Marin, Daniele, et al. “Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results.Radiology, vol. 254, no. 1, Jan. 2010, pp. 179–87. Pubmed, doi:10.1148/radiol.09090486.
Marin D, Soher BJ, Dale BM, Boll DT, Youngblood RS, Merkle EM. Characterization of adrenal lesions: comparison of 2D and 3D dual gradient-echo MR imaging at 3 T--preliminary results. Radiology. 2010 Jan;254(1):179–187.

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

January 2010

Volume

254

Issue

1

Start / End Page

179 / 187

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Retrospective Studies
  • Reference Standards
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Imaging, Three-Dimensional
  • Image Interpretation, Computer-Assisted