Quantitative assay of free and total carnitine using tandem mass spectrometry.
Publication
, Journal Article
Kodo, N; Millington, DS; Norwood, DL; Roe, CR
Published in: Clin Chim Acta
January 31, 1990
A new, specific method for isotope dilution assay of total and free carnitine in urine has been developed. The method utilizes fast atom bombardment ionization with tandem mass spectrometry and requires minimal sample preparation. It compared well with radioenzymatic assay in terms of specificity, precision and accuracy, but was much more convenient in terms of analysis time and sample throughput. The new method is also applicable to the determination of free and short-chain total carnitine in plasma.
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Published In
Clin Chim Acta
DOI
ISSN
0009-8981
Publication Date
January 31, 1990
Volume
186
Issue
3
Start / End Page
383 / 390
Location
Netherlands
Related Subject Headings
- Reproducibility of Results
- Radioligand Assay
- Mass Spectrometry
- Humans
- General Clinical Medicine
- Carnitine
- 3202 Clinical sciences
- 3101 Biochemistry and cell biology
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kodo, N., Millington, D. S., Norwood, D. L., & Roe, C. R. (1990). Quantitative assay of free and total carnitine using tandem mass spectrometry. Clin Chim Acta, 186(3), 383–390. https://doi.org/10.1016/0009-8981(90)90324-l
Kodo, N., D. S. Millington, D. L. Norwood, and C. R. Roe. “Quantitative assay of free and total carnitine using tandem mass spectrometry.” Clin Chim Acta 186, no. 3 (January 31, 1990): 383–90. https://doi.org/10.1016/0009-8981(90)90324-l.
Kodo N, Millington DS, Norwood DL, Roe CR. Quantitative assay of free and total carnitine using tandem mass spectrometry. Clin Chim Acta. 1990 Jan 31;186(3):383–90.
Kodo, N., et al. “Quantitative assay of free and total carnitine using tandem mass spectrometry.” Clin Chim Acta, vol. 186, no. 3, Jan. 1990, pp. 383–90. Pubmed, doi:10.1016/0009-8981(90)90324-l.
Kodo N, Millington DS, Norwood DL, Roe CR. Quantitative assay of free and total carnitine using tandem mass spectrometry. Clin Chim Acta. 1990 Jan 31;186(3):383–390.
Published In
Clin Chim Acta
DOI
ISSN
0009-8981
Publication Date
January 31, 1990
Volume
186
Issue
3
Start / End Page
383 / 390
Location
Netherlands
Related Subject Headings
- Reproducibility of Results
- Radioligand Assay
- Mass Spectrometry
- Humans
- General Clinical Medicine
- Carnitine
- 3202 Clinical sciences
- 3101 Biochemistry and cell biology
- 1103 Clinical Sciences