Hematopoietic cell infusion for the treatment of nuclear disaster victims: new data from the Chernobyl accident.
PURPOSE: To present previously unavailable data on the use of stem cell administration to aid recovery of victims of the Chernobyl disaster. On 26 April 1986, an accident at Unit 4 of the Chernobyl Nuclear Power Plant took place during the planned test of one of the safety systems. The diagnosis of acute radiation syndrome (ARS) was confirmed in 134 individuals exposed to high levels of radiation. There were nine patients heretofore unreported in the scientific literature who underwent intraosseous injections of allogeneic bone marrow cells in Kyiv. CONCLUSIONS: Transplantation was associated with significantly shortened time to recovery of granulocyte and platelet counts in these patients. While current guidelines would certainly include the use of cytokines, these data provide an indication of the effectiveness of stem cell transplant to treat victims of radiation exposure.
Duke Scholars
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Related Subject Headings
- Young Adult
- Treatment Outcome
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Hematopoietic Stem Cell Transplantation
- Chernobyl Nuclear Accident
- Adult
- Acute Radiation Syndrome
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Young Adult
- Treatment Outcome
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Hematopoietic Stem Cell Transplantation
- Chernobyl Nuclear Accident
- Adult
- Acute Radiation Syndrome