Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA.
Publication
, Journal Article
Wilson, KH
Published in: Clin Infect Dis
June 1994
Molecular phylogeny is profoundly influencing the field of bacterial evolution. New knowledge in this area has led to an exciting ability to detect and classify bacteria without culturing them. The process involved consists of either amplification or cloning of ribosomal DNA from a bacterial population, sequencing of this ribosomal DNA, and phylogenetic analysis of the sequences obtained. This approach has so far been applied successfully to four infectious diseases: bacillary angiomatosis, human ehrlichiosis, Whipple's disease, and Tyzzer's disease. Interpretation of data obtained by this method has been straightforward.
Duke Scholars
Published In
Clin Infect Dis
DOI
ISSN
1058-4838
Publication Date
June 1994
Volume
18
Issue
6
Start / End Page
958 / 962
Location
United States
Related Subject Headings
- Whipple Disease
- Polymerase Chain Reaction
- Microbiology
- Humans
- Ehrlichiosis
- DNA, Ribosomal
- DNA, Bacterial
- Bacterial Infections
- Bacteria
- Angiomatosis, Bacillary
Citation
APA
Chicago
ICMJE
MLA
NLM
Wilson, K. H. (1994). Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA. Clin Infect Dis, 18(6), 958–962. https://doi.org/10.1093/clinids/18.6.958
Wilson, K. H. “Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA.” Clin Infect Dis 18, no. 6 (June 1994): 958–62. https://doi.org/10.1093/clinids/18.6.958.
Wilson KH. Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA. Clin Infect Dis. 1994 Jun;18(6):958–62.
Wilson, K. H. “Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA.” Clin Infect Dis, vol. 18, no. 6, June 1994, pp. 958–62. Pubmed, doi:10.1093/clinids/18.6.958.
Wilson KH. Detection of culture-resistant bacterial pathogens by amplification and sequencing of ribosomal DNA. Clin Infect Dis. 1994 Jun;18(6):958–962.
Published In
Clin Infect Dis
DOI
ISSN
1058-4838
Publication Date
June 1994
Volume
18
Issue
6
Start / End Page
958 / 962
Location
United States
Related Subject Headings
- Whipple Disease
- Polymerase Chain Reaction
- Microbiology
- Humans
- Ehrlichiosis
- DNA, Ribosomal
- DNA, Bacterial
- Bacterial Infections
- Bacteria
- Angiomatosis, Bacillary