Computerized detection of masses in digital mammograms: analysis of bilateral subtraction images.
A computerized scheme is being developed for the detection of masses in digital mammograms. Based on the deviation from the normal architectural symmetry of the right and left breasts, a bilateral subtraction technique is used to enhance the conspicuity of possible masses. The scheme employs two pairs of conventional screen-film mammograms (the right and left mediolateral oblique views and craniocaudal views), which are digitized by a TV camera/Gould digitizer. The right and left breast images in each pair are aligned manually during digitization. A nonlinear bilateral subtraction technique that involves linking multiple subtracted images has been investigated and compared to a simple linear subtraction method. Various feature-extraction techniques are used to reduce false-positive detections resulting from the bilateral subtraction. The scheme has been evaluated using 46 pairs of clinical mammograms and was found to yield a 95% true-positive rate at an average of three false-positive detections per image. This preliminary study indicates that the scheme is potentially useful as an aid to radiologists in the interpretation of screening mammograms.
Duke Scholars
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Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Mass Screening
- Mammography
- Humans
- Female
- False Positive Reactions
- Diagnosis, Computer-Assisted
- Databases, Bibliographic
- Breast Neoplasms
- 5105 Medical and biological physics
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Mass Screening
- Mammography
- Humans
- Female
- False Positive Reactions
- Diagnosis, Computer-Assisted
- Databases, Bibliographic
- Breast Neoplasms
- 5105 Medical and biological physics