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Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure.

Publication ,  Journal Article
Gattis, WA; O'Connor, CM
Published in: Am J Cardiol
May 6, 2004

The use of beta-blockers for the treatment of heart failure in the United States is inadequate, despite available data and current guidelines that support their use. The Initiation Management Predischarge: Process for Assessment of Carvedilol Therapy for Heart Failure (IMPACT-HF) study was designed to determine whether initiation of beta-blockade before hospital discharge is safe and effective in improving the 60-day use of beta-blockers in patients with heart failure. IMPACT-HF compared the strategy of the initiation of carvedilol before patients were discharged versus usual care (Heart Failure Society of America guidelines recommend waiting 2 to 4 weeks after hospitalization for heart failure before initiating beta-blocker therapy) in 363 randomized patients with heart failure. The entry criteria were non-restrictive to ensure inclusion of patients reflective of the general heart failure population. The primary end point of the study (the number of patients treated with any beta-blocker at 60 days) was statistically significantly higher in the predischarge group versus the postdischarge group (91.2% vs 73.4%, respectively). Based on the study's results, predischarge initiation may be a successful strategy to improve the use of beta-blocker therapy for patients with heart failure.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 6, 2004

Volume

93

Issue

9A

Start / End Page

74B / 76B

Location

United States

Related Subject Headings

  • Time Factors
  • Survival Rate
  • Prospective Studies
  • Propanolamines
  • Patient Selection
  • Patient Discharge
  • Middle Aged
  • Male
  • Humans
  • Hospitalization
 

Citation

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ICMJE
MLA
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Gattis, W. A., & O’Connor, C. M. (2004). Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure. Am J Cardiol, 93(9A), 74B-76B. https://doi.org/10.1016/j.amjcard.2004.01.019
Gattis, Wendy A., and Christopher M. O’Connor. “Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure.Am J Cardiol 93, no. 9A (May 6, 2004): 74B-76B. https://doi.org/10.1016/j.amjcard.2004.01.019.
Gattis WA, O’Connor CM. Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure. Am J Cardiol. 2004 May 6;93(9A):74B-76B.
Gattis, Wendy A., and Christopher M. O’Connor. “Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure.Am J Cardiol, vol. 93, no. 9A, May 2004, pp. 74B-76B. Pubmed, doi:10.1016/j.amjcard.2004.01.019.
Gattis WA, O’Connor CM. Predischarge initiation of carvedilol in patients hospitalized for decompensated heart failure. Am J Cardiol. 2004 May 6;93(9A):74B-76B.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

May 6, 2004

Volume

93

Issue

9A

Start / End Page

74B / 76B

Location

United States

Related Subject Headings

  • Time Factors
  • Survival Rate
  • Prospective Studies
  • Propanolamines
  • Patient Selection
  • Patient Discharge
  • Middle Aged
  • Male
  • Humans
  • Hospitalization