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Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).

Publication ,  Journal Article
Fonarow, GC; Abraham, WT; Albert, NM; Stough, WG; Gheorghiade, M; Greenberg, BH; O'Connor, CM; Sun, JL; Yancy, C; Young, JB ...
Published in: Am J Cardiol
July 1, 2009

Previous studies have suggested that female and elderly patients with heart failure (HF) are less likely to receive guideline-recommended therapies, but these studies have involved select patient populations. We evaluated the differences in medical care and patient outcomes by age and gender among a broad cohort of hospitalized patients with HF. The Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF) is a registry and performance-improvement program involving 48,612 patients with HF from 259 hospitals. The data were analyzed by gender, age <75 years, and age > or =75 years. Appropriate angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and beta-blocker use were similar between women and men (p = 0.244 and p = 0.237, respectively). However, compared with men, fewer women received hospital discharge instructions (p <0.001) and the length of stay was longer (p <0.001). Risk-adjusted in-hospital and postdischarge mortality were similar. All guideline-recommended cardiac medications were prescribed less frequently at discharge to eligible patients > or =75 than to those <75 years (all p <0.001). Older age was independently associated with in-hospital and postdischarge mortality risk increases (76% and 62%, respectively; p <0.001 for both). In conclusion, among the OPTIMIZE-HF hospitals, female patients with HF generally received similar medical care and had similar risks of adverse clinical outcomes compared with male patients. Older patients with HF were less likely to receive guideline-recommended therapies and remained at greater risk of adverse outcomes.

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Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

July 1, 2009

Volume

104

Issue

1

Start / End Page

107 / 115

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Sex Factors
  • Risk Assessment
  • Quality of Health Care
  • Odds Ratio
  • Male
  • Length of Stay
  • Humans
  • Hospitalization
 

Citation

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Fonarow, G. C., Abraham, W. T., Albert, N. M., Stough, W. G., Gheorghiade, M., Greenberg, B. H., … OPTIMIZE-HF Investigators and Hospitals, . (2009). Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF). Am J Cardiol, 104(1), 107–115. https://doi.org/10.1016/j.amjcard.2009.02.057
Fonarow, Gregg C., William T. Abraham, Nancy M. Albert, Wendy Gattis Stough, Mihai Gheorghiade, Barry H. Greenberg, Christopher M. O’Connor, et al. “Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).Am J Cardiol 104, no. 1 (July 1, 2009): 107–15. https://doi.org/10.1016/j.amjcard.2009.02.057.
Fonarow GC, Abraham WT, Albert NM, Stough WG, Gheorghiade M, Greenberg BH, et al. Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF). Am J Cardiol. 2009 Jul 1;104(1):107–15.
Fonarow, Gregg C., et al. “Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF).Am J Cardiol, vol. 104, no. 1, July 2009, pp. 107–15. Pubmed, doi:10.1016/j.amjcard.2009.02.057.
Fonarow GC, Abraham WT, Albert NM, Stough WG, Gheorghiade M, Greenberg BH, O’Connor CM, Sun JL, Yancy C, Young JB, OPTIMIZE-HF Investigators and Hospitals. Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF). Am J Cardiol. 2009 Jul 1;104(1):107–115.
Journal cover image

Published In

Am J Cardiol

DOI

EISSN

1879-1913

Publication Date

July 1, 2009

Volume

104

Issue

1

Start / End Page

107 / 115

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Sex Factors
  • Risk Assessment
  • Quality of Health Care
  • Odds Ratio
  • Male
  • Length of Stay
  • Humans
  • Hospitalization