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Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes.

Publication ,  Journal Article
Yoo, S; Wu, QJ; Lee, WR; Yin, F-F
Published in: Int J Radiat Oncol Biol Phys
March 1, 2010

PURPOSE: Dosimetric results and treatment delivery efficiency of RapidArc plans to those of conventional intensity-modulated radiotherapy (IMRT) plans were compared using the Eclipse treatment planning system for high-risk prostate cancer. MATERIALS AND METHODS: This study included 10 patients. The primary planning target volume (PTV(P)) contained prostate, seminal vesicles, and pelvic lymph nodes with a margin. The boost PTV (PTV(B)) contained prostate and seminal vesicles with a margin. The total prescription dose was 75.6 Gy (46.8 Gy to PTV(P) and an additional 28.8 Gy to PTV(B); 1.8 Gy/fraction). Three plans were generated for each PTV: Multiple-field IMRT, one-arc RapidArc (1ARC), and two-arc RapidArc (2ARC). RESULTS: In the primary IMRT with PTV(P), average mean doses to bladder, rectum and small bowel were lower by 5.9%, 7.7% and 4.3%, respectively, than in the primary 1ARC and by 3.6%, 4.8% and 3.1%, respectively, than in the primary 2ARC. In the boost IMRT with PTV(B), average mean doses to bladder and rectum were lower by 2.6% and 4.8% than with the boost 1ARC and were higher by 0.6% and 0.2% than with the boost 2ARC. Integral doses were 7% to 9% higher with RapidArc than with IMRT for both primary and boost plans. Treatment delivery time was reduced by 2-7 minutes using RapidArc. CONCLUSION: For PTVs including prostate, seminal vesicles, and lymph nodes, IMRT performed better in dose sparing for bladder, rectum, and small bowel than did RapidArc. For PTVs including prostate and seminal vesicles, RapidArc with two arcs provided plans comparable to those for IMRT. The treatment delivery is more efficient with RapidArc.

Duke Scholars

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

March 1, 2010

Volume

76

Issue

3

Start / End Page

935 / 942

Location

United States

Related Subject Headings

  • Urinary Bladder
  • Seminal Vesicles
  • Rectum
  • Radiotherapy, Intensity-Modulated
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Radiography
  • Radiation Injuries
  • Prostatic Neoplasms
  • Prostate
 

Citation

APA
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ICMJE
MLA
NLM
Yoo, S., Wu, Q. J., Lee, W. R., & Yin, F.-F. (2010). Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. Int J Radiat Oncol Biol Phys, 76(3), 935–942. https://doi.org/10.1016/j.ijrobp.2009.07.1677
Yoo, Sua, Q Jackie Wu, W Robert Lee, and Fang-Fang Yin. “Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes.Int J Radiat Oncol Biol Phys 76, no. 3 (March 1, 2010): 935–42. https://doi.org/10.1016/j.ijrobp.2009.07.1677.
Yoo S, Wu QJ, Lee WR, Yin F-F. Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):935–42.
Yoo, Sua, et al. “Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes.Int J Radiat Oncol Biol Phys, vol. 76, no. 3, Mar. 2010, pp. 935–42. Pubmed, doi:10.1016/j.ijrobp.2009.07.1677.
Yoo S, Wu QJ, Lee WR, Yin F-F. Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):935–942.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

March 1, 2010

Volume

76

Issue

3

Start / End Page

935 / 942

Location

United States

Related Subject Headings

  • Urinary Bladder
  • Seminal Vesicles
  • Rectum
  • Radiotherapy, Intensity-Modulated
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Radiography
  • Radiation Injuries
  • Prostatic Neoplasms
  • Prostate