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Accelerating phase contrast MR angiography by simplified skipped phase encoding and edge deghosting with array coil enhancement.

Publication ,  Journal Article
Chang, Z; Xiang, Q-S; Shen, H; Ji, J; Yin, F-F
Published in: Med Phys
March 2012

PURPOSE: The aim of this work is to investigate the feasibility of accelerating phase contrast magnetic resonance angiography (PC-MRA) by the fast imaging method of simplified skipped phase encoding and edge deghosting with array coil enhancement (S-SPEED-ACE). METHODS: The parallel imaging method of skipped phase encoding and edge deghosting with array coil enhancement (SPEED-ACE) is simplified for imaging sparse objects like phase contrast MRA. This approach is termed S-SPEED-ACE in which k-space is sparsely sampled with skipped phase encoding at every Nth step using multiple receiver coils simultaneously. The sampled data are then Fourier transformed into a set of ghosted images, each with N-fold aliasing ghosts. Given signal sparseness of MRA, the ghosted images are modeled with a single-layer structure, in which the most dominant ghost within the potentially overlapped ghosts at each pixel is selected to represent the signal of that pixel. The single-layer model is analogous to that used in maximum-intensity-projection (MIP) that selects only the brightest signal even when there are overlapped vessels. With an algorithm based on a least-square-error solution, a deghosted image is obtained, along with a residual map for quality control. In this way, S-SPEED-ACE partially samples k-space using multiple receiver coils in parallel, and yields a deghosted image with an acceleration factor of N. Without full central k-space sampling and differential filtering, S-SPEED-ACE achieves further scan time reduction with a more straightforward reconstruction. In this work, S-SPEED-ACE is demonstrated to accelerate a computer simulated PC-MRA and a real human 3D PC-MRA, which was acquired using a clinical 1.5 T scanner on a healthy volunteer. RESULTS: Images are reconstructed by S-SPEED-ACE to achieve an undersampling factor of up to 8.3 with four receiver coils. The reconstructed images generally have comparable quality as that of the reference images reconstructed from full k-space data. Maximum-intensity-projection images generated from the reconstructed images also demonstrated to be consistent as those from the reference images. CONCLUSIONS: By taking advantage of signal sparsity naturally existing in the data, SPEED-ACE was simplified and its efficiency was improved. The feasibility of the proposed S-SPEED-ACE is demonstrated in this work with simulated sampling of an actual 3D head PC-MRA scan.

Duke Scholars

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

March 2012

Volume

39

Issue

3

Start / End Page

1247 / 1252

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Angiography
  • Image Processing, Computer-Assisted
  • Humans
  • Feasibility Studies
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chang, Z., Xiang, Q.-S., Shen, H., Ji, J., & Yin, F.-F. (2012). Accelerating phase contrast MR angiography by simplified skipped phase encoding and edge deghosting with array coil enhancement. Med Phys, 39(3), 1247–1252. https://doi.org/10.1118/1.3682000
Chang, Zheng, Qing-San Xiang, Hao Shen, Jim Ji, and Fang-Fang Yin. “Accelerating phase contrast MR angiography by simplified skipped phase encoding and edge deghosting with array coil enhancement.Med Phys 39, no. 3 (March 2012): 1247–52. https://doi.org/10.1118/1.3682000.
Chang, Zheng, et al. “Accelerating phase contrast MR angiography by simplified skipped phase encoding and edge deghosting with array coil enhancement.Med Phys, vol. 39, no. 3, Mar. 2012, pp. 1247–52. Pubmed, doi:10.1118/1.3682000.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

March 2012

Volume

39

Issue

3

Start / End Page

1247 / 1252

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Angiography
  • Image Processing, Computer-Assisted
  • Humans
  • Feasibility Studies
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences