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Automatic registration between reference and on-board digital tomosynthesis images for positioning verification.

Publication ,  Journal Article
Ren, L; Godfrey, DJ; Yan, H; Wu, QJ; Yin, F-F
Published in: Med Phys
February 2008

The authors developed a hybrid multiresolution rigid-body registration technique to automatically register reference digital tomosynthesis (DTS) images with on-board DTS images to guide patient positioning in radiation therapy. This hybrid registration technique uses a faster but less accurate static method to achieve an initial registration, followed by a slower but more accurate adaptive method to fine tune the registration. A multiresolution scheme is employed in the registration to further improve the registration accuracy, robustness, and efficiency. Normalized mutual information is selected as the criterion for the similarity measure and the downhill simplex method is used as the search engine. This technique was tested using image data both from an anthropomorphic chest phantom and from eight head-and-neck cancer patients. The effects of the scan angle and the region-of-interest (ROI) size on the registration accuracy and robustness were investigated. The necessity of using the adaptive registration method in the hybrid technique was validated by comparing the results of the static method and the hybrid method. With a 44 degrees scan angle and a large ROI covering the entire DTS volume, the average of the registration capture ranges in single-axis simulations was between -31 and +34 deg for rotations and between -89 and +78 mm for translations in the phantom study, and between -38 and +38 deg for rotations and between -58 and +65 mm for translations in the patient study. Decreasing the DTS scan angle from 44 degrees to 22 degrees mainly degraded the registration accuracy and robustness for the out-of-plane rotations. Decreasing the ROI size from the entire DTS volume to the volume surrounding the spinal cord reduced the capture ranges to between -23 and +18 deg for rotations and between -33 and +43 mm for translations in the phantom study, and between -18 and +25 deg for rotations and between -35 and +39 mm for translations in the patient study. Results also showed that the hybrid registration technique had much larger capture ranges than the static method alone in registering the out-of-plane rotations.

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Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

February 2008

Volume

35

Issue

2

Start / End Page

664 / 672

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Subtraction Technique
  • Signal Processing, Computer-Assisted
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Reference Values
  • Radiotherapy, Conformal
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Posture
 

Citation

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Ren, L., Godfrey, D. J., Yan, H., Wu, Q. J., & Yin, F.-F. (2008). Automatic registration between reference and on-board digital tomosynthesis images for positioning verification. Med Phys, 35(2), 664–672. https://doi.org/10.1118/1.2831903
Ren, Lei, Devon J. Godfrey, Hui Yan, Q Jackie Wu, and Fang-Fang Yin. “Automatic registration between reference and on-board digital tomosynthesis images for positioning verification.Med Phys 35, no. 2 (February 2008): 664–72. https://doi.org/10.1118/1.2831903.
Ren L, Godfrey DJ, Yan H, Wu QJ, Yin F-F. Automatic registration between reference and on-board digital tomosynthesis images for positioning verification. Med Phys. 2008 Feb;35(2):664–72.
Ren, Lei, et al. “Automatic registration between reference and on-board digital tomosynthesis images for positioning verification.Med Phys, vol. 35, no. 2, Feb. 2008, pp. 664–72. Pubmed, doi:10.1118/1.2831903.
Ren L, Godfrey DJ, Yan H, Wu QJ, Yin F-F. Automatic registration between reference and on-board digital tomosynthesis images for positioning verification. Med Phys. 2008 Feb;35(2):664–672.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

February 2008

Volume

35

Issue

2

Start / End Page

664 / 672

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Subtraction Technique
  • Signal Processing, Computer-Assisted
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Reference Values
  • Radiotherapy, Conformal
  • Radiographic Image Interpretation, Computer-Assisted
  • Radiographic Image Enhancement
  • Posture