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Incidence of retinopathy of prematurity in the United States: 1997 through 2005.

Publication ,  Journal Article
Lad, EM; Hernandez-Boussard, T; Morton, JM; Moshfeghi, DM
Published in: Am J Ophthalmol
September 2009

PURPOSE: To determine the incidence of retinopathy of prematurity (ROP) based on a national database and to identify baseline characteristics, demographic information, comorbidities, and surgical interventions. DESIGN: Retrospective study based on the National Inpatient Sample from 1997 through 2005. METHODS: The National Inpatient Sample was queried for all newborn infants with and without ROP. Multivariate logistic regression was used to predict risk factors for ROP. RESULTS: Thirty-four million live births were recorded during the study period. The total ROP incidence was 0.17% overall and 15.58% for premature infants with length of stay of more than 28 days. Our results conclusively demonstrated the importance of low birth weight as a risk for ROP development in infants with length of stay of more than 28 days, as well as association with respiratory conditions, fetal hemorrhage, intraventricular hemorrhage, and blood transfer. An interesting finding was the protective effect conferred by hypoxia, necrotizing enterocolitis, and hemolytic disease of the newborn. Infants with ROP had a higher incidence of undergoing laser photocoagulation therapy, pars plana vitrectomy, and scleral buckle surgery. CONCLUSIONS: The current study represents a large, retrospective analysis of newborns with ROP. The multivariate analysis emphasizes the role of birth weight in extended-stay infants, as well as respiratory conditions, fetal hemorrhage, intraventricular hemorrhage, and blood transfer.

Duke Scholars

Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

September 2009

Volume

148

Issue

3

Start / End Page

451 / 458

Location

United States

Related Subject Headings

  • United States
  • Risk Factors
  • Retrospective Studies
  • Retinopathy of Prematurity
  • Ophthalmology & Optometry
  • Odds Ratio
  • Multivariate Analysis
  • Male
  • Infant, Newborn
  • Incidence
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lad, E. M., Hernandez-Boussard, T., Morton, J. M., & Moshfeghi, D. M. (2009). Incidence of retinopathy of prematurity in the United States: 1997 through 2005. Am J Ophthalmol, 148(3), 451–458. https://doi.org/10.1016/j.ajo.2009.04.018
Lad, Eleonora M., Tina Hernandez-Boussard, John M. Morton, and Darius M. Moshfeghi. “Incidence of retinopathy of prematurity in the United States: 1997 through 2005.Am J Ophthalmol 148, no. 3 (September 2009): 451–58. https://doi.org/10.1016/j.ajo.2009.04.018.
Lad EM, Hernandez-Boussard T, Morton JM, Moshfeghi DM. Incidence of retinopathy of prematurity in the United States: 1997 through 2005. Am J Ophthalmol. 2009 Sep;148(3):451–8.
Lad, Eleonora M., et al. “Incidence of retinopathy of prematurity in the United States: 1997 through 2005.Am J Ophthalmol, vol. 148, no. 3, Sept. 2009, pp. 451–58. Pubmed, doi:10.1016/j.ajo.2009.04.018.
Lad EM, Hernandez-Boussard T, Morton JM, Moshfeghi DM. Incidence of retinopathy of prematurity in the United States: 1997 through 2005. Am J Ophthalmol. 2009 Sep;148(3):451–458.
Journal cover image

Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

September 2009

Volume

148

Issue

3

Start / End Page

451 / 458

Location

United States

Related Subject Headings

  • United States
  • Risk Factors
  • Retrospective Studies
  • Retinopathy of Prematurity
  • Ophthalmology & Optometry
  • Odds Ratio
  • Multivariate Analysis
  • Male
  • Infant, Newborn
  • Incidence