Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.
Publication
, Journal Article
Osman, FA; Bier, J; Bier, H; Siegel, T; Maurer, HR; Ohanian, S
Published in: Int J Cell Cloning
June 1983
The effects of intralesional chemotherapy with 7 different drugs on line 10 hepatoma grown in strain 2 guinea pigs were compared with the sensitivity of line 10 tumor cells in vitro, using a micro modification of the tumor stem assay with capillary tubes. A modified method was used to evaluate the in vitro dose-response curves. The correlation for in vivo/in vitro resistance was found to be 100% and for in vivo/in sensitivity it was 80%.
Duke Scholars
Published In
Int J Cell Cloning
DOI
ISSN
0737-1454
Publication Date
June 1983
Volume
1
Issue
2
Start / End Page
118 / 127
Location
United States
Related Subject Headings
- Vincristine
- Stem Cells
- Neoplastic Stem Cells
- Methotrexate
- Liver Neoplasms, Experimental
- Guinea Pigs
- Fluorouracil
- Female
- Drug Evaluation, Preclinical
- Dose-Response Relationship, Drug
Citation
APA
Chicago
ICMJE
MLA
NLM
Osman, F. A., Bier, J., Bier, H., Siegel, T., Maurer, H. R., & Ohanian, S. (1983). Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity. Int J Cell Cloning, 1(2), 118–127. https://doi.org/10.1002/stem.5530010206
Osman, F. A., J. Bier, H. Bier, T. Siegel, H. R. Maurer, and S. Ohanian. “Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.” Int J Cell Cloning 1, no. 2 (June 1983): 118–27. https://doi.org/10.1002/stem.5530010206.
Osman FA, Bier J, Bier H, Siegel T, Maurer HR, Ohanian S. Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity. Int J Cell Cloning. 1983 Jun;1(2):118–27.
Osman, F. A., et al. “Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity.” Int J Cell Cloning, vol. 1, no. 2, June 1983, pp. 118–27. Pubmed, doi:10.1002/stem.5530010206.
Osman FA, Bier J, Bier H, Siegel T, Maurer HR, Ohanian S. Correlation of intralesional in vivo chemotherapy of line 10 hepatoma with in vitro drug sensitivity. Int J Cell Cloning. 1983 Jun;1(2):118–127.
Published In
Int J Cell Cloning
DOI
ISSN
0737-1454
Publication Date
June 1983
Volume
1
Issue
2
Start / End Page
118 / 127
Location
United States
Related Subject Headings
- Vincristine
- Stem Cells
- Neoplastic Stem Cells
- Methotrexate
- Liver Neoplasms, Experimental
- Guinea Pigs
- Fluorouracil
- Female
- Drug Evaluation, Preclinical
- Dose-Response Relationship, Drug