Platelet function monitoring in patients with coronary artery disease.
Publication
, Journal Article
Gurbel, PA; Becker, RC; Mann, KG; Steinhubl, SR; Michelson, AD
Published in: J Am Coll Cardiol
November 6, 2007
Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and clopidogrel, have increased in recent years. However, the relations of in vivo platelet function and adverse clinical events to results of ex vivo platelet function tests remain largely unknown. This article describes current methods of measuring platelet function in various clinical and research situations and their advantages and disadvantages, reviews evidence for antiplatelet response variability and resistance, discusses the potential pitfalls of monitoring platelet function, and demonstrates emerging data supporting the positive clinical and treatment implications of platelet function testing.
Duke Scholars
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Published In
J Am Coll Cardiol
DOI
EISSN
1558-3597
Publication Date
November 6, 2007
Volume
50
Issue
19
Start / End Page
1822 / 1834
Location
United States
Related Subject Headings
- Treatment Outcome
- Ticlopidine
- Risk Factors
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Function Tests
- Platelet Aggregation Inhibitors
- Myocardial Infarction
- Monitoring, Physiologic
- Humans
- Drug Resistance
Citation
APA
Chicago
ICMJE
MLA
NLM
Gurbel, P. A., Becker, R. C., Mann, K. G., Steinhubl, S. R., & Michelson, A. D. (2007). Platelet function monitoring in patients with coronary artery disease. J Am Coll Cardiol, 50(19), 1822–1834. https://doi.org/10.1016/j.jacc.2007.07.051
Gurbel, Paul A., Richard C. Becker, Kenneth G. Mann, Steven R. Steinhubl, and Alan D. Michelson. “Platelet function monitoring in patients with coronary artery disease.” J Am Coll Cardiol 50, no. 19 (November 6, 2007): 1822–34. https://doi.org/10.1016/j.jacc.2007.07.051.
Gurbel PA, Becker RC, Mann KG, Steinhubl SR, Michelson AD. Platelet function monitoring in patients with coronary artery disease. J Am Coll Cardiol. 2007 Nov 6;50(19):1822–34.
Gurbel, Paul A., et al. “Platelet function monitoring in patients with coronary artery disease.” J Am Coll Cardiol, vol. 50, no. 19, Nov. 2007, pp. 1822–34. Pubmed, doi:10.1016/j.jacc.2007.07.051.
Gurbel PA, Becker RC, Mann KG, Steinhubl SR, Michelson AD. Platelet function monitoring in patients with coronary artery disease. J Am Coll Cardiol. 2007 Nov 6;50(19):1822–1834.
Published In
J Am Coll Cardiol
DOI
EISSN
1558-3597
Publication Date
November 6, 2007
Volume
50
Issue
19
Start / End Page
1822 / 1834
Location
United States
Related Subject Headings
- Treatment Outcome
- Ticlopidine
- Risk Factors
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Function Tests
- Platelet Aggregation Inhibitors
- Myocardial Infarction
- Monitoring, Physiologic
- Humans
- Drug Resistance