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Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation

Publication ,  Journal Article
Li, J; Jaszczak, RJ; Coleman, RE
Published in: IEEE Transactions on Nuclear Science
January 1, 1995

A quantitative filtered backprojection (FBP) algorithm for small field-of-view pinhole SPECT has been implemented and evaluated. This algorithm compensates for attenuation, scatter, geometric collimator response and system misalignment. Pinhole SPECT quantification with three different pinhole collimators was evaluated using experimentally acquired phantom data. SPECT scans using both in-air and in-water point sources located at different places and a cylinder filled with uniform activity were acquired. Planar scans of an in-air point source from different incident angles were acquired to determine the angular dependence of the geometric collimator response. Images were reconstructed using the FBP algorithm, with geometric response correction, dual-window scatter subtraction (c = 0.4), single iteration Chang attenuation compensation, and system misalignment correction. Total activities in point source experiments and concentrations in cylindrical phantom experiments were measured. Accurate quantitative results (<7%) were obtained using the pinhole FBP algorithm. © 1995 IEEE.

Duke Scholars

Published In

IEEE Transactions on Nuclear Science

DOI

EISSN

1558-1578

ISSN

0018-9499

Publication Date

January 1, 1995

Volume

42

Issue

4

Start / End Page

1109 / 1113

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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MLA
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Li, J., Jaszczak, R. J., & Coleman, R. E. (1995). Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation. IEEE Transactions on Nuclear Science, 42(4), 1109–1113. https://doi.org/10.1109/23.467740
Li, J., R. J. Jaszczak, and R. E. Coleman. “Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation.” IEEE Transactions on Nuclear Science 42, no. 4 (January 1, 1995): 1109–13. https://doi.org/10.1109/23.467740.
Li J, Jaszczak RJ, Coleman RE. Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation. IEEE Transactions on Nuclear Science. 1995 Jan 1;42(4):1109–13.
Li, J., et al. “Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation.” IEEE Transactions on Nuclear Science, vol. 42, no. 4, Jan. 1995, pp. 1109–13. Scopus, doi:10.1109/23.467740.
Li J, Jaszczak RJ, Coleman RE. Quantitative Small Field-of-View Pinhole SPECT Imaging: Initial Evaluation. IEEE Transactions on Nuclear Science. 1995 Jan 1;42(4):1109–1113.

Published In

IEEE Transactions on Nuclear Science

DOI

EISSN

1558-1578

ISSN

0018-9499

Publication Date

January 1, 1995

Volume

42

Issue

4

Start / End Page

1109 / 1113

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics