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Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan.

Publication ,  Journal Article
Mather-Mihaich, E; Di Giulio, RT
Published in: Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
January 1986

Indicators of free-radical or oxidant-mediated responses were quantified in channel catfish, Ictalurus punctatus, exposed to the organophosphorus herbicide DEF and its metabolite, n-butyl mercaptan (nBM). The activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase did not vary significantly with toxicant or dose. The concentrations of reduced glutathione (GSH) and malondialdehyde (MDA) did not vary significantly with toxicant or dose. The percentage of methemoglobin increased in the nBM-exposed fish with dose, up to 16.5% of total hemoglobin. The DEF-exposed catfish had no significant increases in methemoglobin compared to controls.

Duke Scholars

Published In

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology

DOI

ISSN

0742-8413

Publication Date

January 1986

Volume

85

Issue

2

Start / End Page

427 / 432

Related Subject Headings

  • Superoxide Dismutase
  • Sulfhydryl Compounds
  • Organothiophosphorus Compounds
  • Organothiophosphates
  • Methemoglobin
  • Malondialdehyde
  • Malonates
  • Liver
  • Kinetics
  • Ictaluridae
 

Citation

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Mather-Mihaich, E., & Di Giulio, R. T. (1986). Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology, 85(2), 427–432. https://doi.org/10.1016/0742-8413(86)90220-3
Mather-Mihaich, E., and R. T. Di Giulio. “Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan.Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology 85, no. 2 (January 1986): 427–32. https://doi.org/10.1016/0742-8413(86)90220-3.
Mather-Mihaich E, Di Giulio RT. Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan. Comparative biochemistry and physiology C, Comparative pharmacology and toxicology. 1986 Jan;85(2):427–32.
Mather-Mihaich, E., and R. T. Di Giulio. “Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan.Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology, vol. 85, no. 2, Jan. 1986, pp. 427–32. Epmc, doi:10.1016/0742-8413(86)90220-3.
Mather-Mihaich E, Di Giulio RT. Antioxidant enzyme activities and malondialdehyde, glutathione and methemoglobin concentrations in channel catfish exposed to DEF and n-butyl mercaptan. Comparative biochemistry and physiology C, Comparative pharmacology and toxicology. 1986 Jan;85(2):427–432.

Published In

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology

DOI

ISSN

0742-8413

Publication Date

January 1986

Volume

85

Issue

2

Start / End Page

427 / 432

Related Subject Headings

  • Superoxide Dismutase
  • Sulfhydryl Compounds
  • Organothiophosphorus Compounds
  • Organothiophosphates
  • Methemoglobin
  • Malondialdehyde
  • Malonates
  • Liver
  • Kinetics
  • Ictaluridae