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Angiotensin converting enzyme inhibitors and the cardiovascular system.

Publication ,  Journal Article
Dzau, VJ
Published in: J Hypertens Suppl
June 1992

OBJECTIVE: To show that angiotensin converting enzyme (ACE) inhibitors benefit the cardiovascular system to a greater extent than other antihypertensive agents. DATA EXTRACTION: An extensive literature search has shown that ACE inhibitors can induce regression of left ventricular hypertrophy, which may improve systolic and/or diastolic function in the left ventricle; increase in arterial compliance; and improve clinical signs of congestive heart failure and reduce mortality in patients with severe heart failure. In addition, ACE inhibitors have either a neutral or a beneficial effect on blood lipids and lipoproteins. These agents also have potential anti-ischaemic and anti-arrhythmic activity but do not depress resting cardiac function. CONCLUSION: ACE inhibitors are uniquely valuable first-line antihypertensive agents, especially in patients with cardiovascular risk.

Duke Scholars

Published In

J Hypertens Suppl

ISSN

0952-1178

Publication Date

June 1992

Volume

10

Issue

3

Start / End Page

S3 / 10

Location

England

Related Subject Headings

  • Vascular Resistance
  • Lipoproteins
  • Lipids
  • Hypertension
  • Humans
  • Heart Failure
  • Coronary Disease
  • Cardiovascular System & Hematology
  • Cardiovascular System
  • Cardiomegaly
 

Citation

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ICMJE
MLA
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Dzau, V. J. (1992). Angiotensin converting enzyme inhibitors and the cardiovascular system. J Hypertens Suppl, 10(3), S3-10.
Dzau, V. J. “Angiotensin converting enzyme inhibitors and the cardiovascular system.J Hypertens Suppl 10, no. 3 (June 1992): S3-10.
Dzau VJ. Angiotensin converting enzyme inhibitors and the cardiovascular system. J Hypertens Suppl. 1992 Jun;10(3):S3-10.
Dzau, V. J. “Angiotensin converting enzyme inhibitors and the cardiovascular system.J Hypertens Suppl, vol. 10, no. 3, June 1992, pp. S3-10.
Dzau VJ. Angiotensin converting enzyme inhibitors and the cardiovascular system. J Hypertens Suppl. 1992 Jun;10(3):S3-10.

Published In

J Hypertens Suppl

ISSN

0952-1178

Publication Date

June 1992

Volume

10

Issue

3

Start / End Page

S3 / 10

Location

England

Related Subject Headings

  • Vascular Resistance
  • Lipoproteins
  • Lipids
  • Hypertension
  • Humans
  • Heart Failure
  • Coronary Disease
  • Cardiovascular System & Hematology
  • Cardiovascular System
  • Cardiomegaly