Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses.
Publication
, Journal Article
Dzau, VJ
Published in: J Hypertens
December 1989
In summary, multiple pathways of angiotensin production may exist in the blood vessel wall (Fig. 1), in addition to the well described renin--ACE enzymatic axis. It is not known whether these enzymatic pathways represent in vitro phenomena, or authentic in vivo alternate pathways which are activated only when the renin--ACE pathway is blocked, or whether they are operative at all times in the vessel wall. If these multiple pathways are functional, then the vascular angiotensin system may be very complicated, and may vary in different pathophysiological states. Future research in this area is likely to yield important and novel information on the in vivo pathways of production and function of vascular angiotensin.
Duke Scholars
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Published In
J Hypertens
DOI
ISSN
0263-6352
Publication Date
December 1989
Volume
7
Issue
12
Start / End Page
933 / 936
Location
Netherlands
Related Subject Headings
- Renin-Angiotensin System
- Peptidyl-Dipeptidase A
- Humans
- Endothelium, Vascular
- Cardiovascular System & Hematology
- Angiotensinogen
- Angiotensin II
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology
- 1116 Medical Physiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Dzau, V. J. (1989). Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. J Hypertens, 7(12), 933–936. https://doi.org/10.1097/00004872-198912000-00001
Dzau, V. J. “Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses.” J Hypertens 7, no. 12 (December 1989): 933–36. https://doi.org/10.1097/00004872-198912000-00001.
Dzau VJ. Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. J Hypertens. 1989 Dec;7(12):933–6.
Dzau, V. J. “Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses.” J Hypertens, vol. 7, no. 12, Dec. 1989, pp. 933–36. Pubmed, doi:10.1097/00004872-198912000-00001.
Dzau VJ. Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses. J Hypertens. 1989 Dec;7(12):933–936.
Published In
J Hypertens
DOI
ISSN
0263-6352
Publication Date
December 1989
Volume
7
Issue
12
Start / End Page
933 / 936
Location
Netherlands
Related Subject Headings
- Renin-Angiotensin System
- Peptidyl-Dipeptidase A
- Humans
- Endothelium, Vascular
- Cardiovascular System & Hematology
- Angiotensinogen
- Angiotensin II
- 3202 Clinical sciences
- 3201 Cardiovascular medicine and haematology
- 1116 Medical Physiology