Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection.
Publication
, Journal Article
Lipsky, MM; Hinton, DE; Goldblatt, PJ; Klaunig, JE; Trump, BF
Published in: Pathology, research and practice
May 1979
A procedure for the production of mouse hepatic siderosis is described which results in extensive iron deposition in all lobular zones. Mice exposed to safrole for 24 weeks displayed basophilic and acidophilic foci which did not accumulate iron. 36 weeks of dietary safrole exposure resulted in nodular lesions comprised of basophilic and hyalinized cells. The nodules displayed decreased or negative reactions for iron in hepatic parenchymal cells when the surrounding liver was siderotic.
Duke Scholars
Published In
Pathology, research and practice
DOI
EISSN
1618-0631
ISSN
0344-0338
Publication Date
May 1979
Volume
164
Issue
2
Start / End Page
178 / 185
Related Subject Headings
- Siderosis
- Safrole
- Precancerous Conditions
- Pathology
- Mice, Inbred BALB C
- Mice
- Male
- Liver Neoplasms
- Liver
- Kupffer Cells
Citation
APA
Chicago
ICMJE
MLA
NLM
Lipsky, M. M., Hinton, D. E., Goldblatt, P. J., Klaunig, J. E., & Trump, B. F. (1979). Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection. Pathology, Research and Practice, 164(2), 178–185. https://doi.org/10.1016/s0344-0338(79)80022-9
Lipsky, M. M., D. E. Hinton, P. J. Goldblatt, J. E. Klaunig, and B. F. Trump. “Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection.” Pathology, Research and Practice 164, no. 2 (May 1979): 178–85. https://doi.org/10.1016/s0344-0338(79)80022-9.
Lipsky MM, Hinton DE, Goldblatt PJ, Klaunig JE, Trump BF. Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection. Pathology, research and practice. 1979 May;164(2):178–85.
Lipsky, M. M., et al. “Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection.” Pathology, Research and Practice, vol. 164, no. 2, May 1979, pp. 178–85. Epmc, doi:10.1016/s0344-0338(79)80022-9.
Lipsky MM, Hinton DE, Goldblatt PJ, Klaunig JE, Trump BF. Iron negative foci and nodules in safrole-exposed mouse liver made siderotic by iron-dextran injection. Pathology, research and practice. 1979 May;164(2):178–185.
Published In
Pathology, research and practice
DOI
EISSN
1618-0631
ISSN
0344-0338
Publication Date
May 1979
Volume
164
Issue
2
Start / End Page
178 / 185
Related Subject Headings
- Siderosis
- Safrole
- Precancerous Conditions
- Pathology
- Mice, Inbred BALB C
- Mice
- Male
- Liver Neoplasms
- Liver
- Kupffer Cells