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Chronic lymphocytic leukemia in African Americans.

Publication ,  Journal Article
Coombs, CC; Falchi, L; Weinberg, JB; Ferrajoli, A; Lanasa, MC
Published in: Leuk Lymphoma
November 2012

Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia in the United States with almost 4390 attributable deaths per year. Epidemiologic data compiled by the Surveillance, Epidemiology and End Results (SEER) program identifies important differences in incidence and survival for African Americans with CLL. Although the incidence of CLL is lower among African Americans than among Caucasians (4.6 and 6.2 per 100 000 men, respectively), age-adjusted survival is inferior. African American patients with CLL are almost twice as likely to die from a CLL-related complication in the first 5 years after diagnosis as are Caucasian patients with CLL. The biologic basis for these observations is almost entirely unexplored, and a comprehensive clinical analysis of African American patients with CLL is lacking. This is the subject of the present review.

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Published In

Leuk Lymphoma

DOI

EISSN

1029-2403

Publication Date

November 2012

Volume

53

Issue

11

Start / End Page

2326 / 2329

Location

United States

Related Subject Headings

  • SEER Program
  • Polymorphism, Single Nucleotide
  • Male
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Immunology
  • Humans
  • Female
  • Black or African American
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

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MLA
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Coombs, C. C., Falchi, L., Weinberg, J. B., Ferrajoli, A., & Lanasa, M. C. (2012). Chronic lymphocytic leukemia in African Americans. Leuk Lymphoma, 53(11), 2326–2329. https://doi.org/10.3109/10428194.2012.698276
Coombs, Catherine C., Lorenzo Falchi, J Brice Weinberg, Alessandra Ferrajoli, and Mark C. Lanasa. “Chronic lymphocytic leukemia in African Americans.Leuk Lymphoma 53, no. 11 (November 2012): 2326–29. https://doi.org/10.3109/10428194.2012.698276.
Coombs CC, Falchi L, Weinberg JB, Ferrajoli A, Lanasa MC. Chronic lymphocytic leukemia in African Americans. Leuk Lymphoma. 2012 Nov;53(11):2326–9.
Coombs, Catherine C., et al. “Chronic lymphocytic leukemia in African Americans.Leuk Lymphoma, vol. 53, no. 11, Nov. 2012, pp. 2326–29. Pubmed, doi:10.3109/10428194.2012.698276.
Coombs CC, Falchi L, Weinberg JB, Ferrajoli A, Lanasa MC. Chronic lymphocytic leukemia in African Americans. Leuk Lymphoma. 2012 Nov;53(11):2326–2329.

Published In

Leuk Lymphoma

DOI

EISSN

1029-2403

Publication Date

November 2012

Volume

53

Issue

11

Start / End Page

2326 / 2329

Location

United States

Related Subject Headings

  • SEER Program
  • Polymorphism, Single Nucleotide
  • Male
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Immunology
  • Humans
  • Female
  • Black or African American
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences