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A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives

Publication ,  Journal Article
Guy, W; Ban, TA; McEvoy, JP; Petrie, WM; Wilson, WH; Schaffer, JD
Published in: International Pharmacopsychiatry
1982

In a multicenter series of trials, viloxazine was compared with imipramine, amitriptyline, doxepin and placebo in 123 neurotic and endogenous depressive inpatients and outpatients. While significant period effects reflecting improvement were obtained on the majority of efficacy variables, no significant differences were obtained among the treatment groups or depressive types. Imipramine and amitriptyline exhibited more anticholinergic adverse reactions; while, viloxazine exhibited greater CNS effects. Dizziness and nausea were much more frequent in neurotic depressives which may be related to their psychopathology.

Duke Scholars

Published In

International Pharmacopsychiatry

ISSN

0020-8272

Publication Date

1982

Volume

17

Issue

1

Start / End Page

36 / 42

Related Subject Headings

  • Psychiatry
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
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ICMJE
MLA
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Guy, W., Ban, T. A., McEvoy, J. P., Petrie, W. M., Wilson, W. H., & Schaffer, J. D. (1982). A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives. International Pharmacopsychiatry, 17(1), 36–42.
Guy, W., T. A. Ban, J. P. McEvoy, W. M. Petrie, W. H. Wilson, and J. D. Schaffer. “A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.” International Pharmacopsychiatry 17, no. 1 (1982): 36–42.
Guy W, Ban TA, McEvoy JP, Petrie WM, Wilson WH, Schaffer JD. A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives. International Pharmacopsychiatry. 1982;17(1):36–42.
Guy, W., et al. “A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives.” International Pharmacopsychiatry, vol. 17, no. 1, 1982, pp. 36–42.
Guy W, Ban TA, McEvoy JP, Petrie WM, Wilson WH, Schaffer JD. A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives. International Pharmacopsychiatry. 1982;17(1):36–42.

Published In

International Pharmacopsychiatry

ISSN

0020-8272

Publication Date

1982

Volume

17

Issue

1

Start / End Page

36 / 42

Related Subject Headings

  • Psychiatry
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences