Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells
Publication
, Journal Article
Newgard, CB
Published in: Diabetes Reviews
January 1, 1996
Insulin secretion is largely controlled by the level of circulating glucose. The mechanism by which glucose stimulates insulin release from pancreatic islet β-cells has been an important but difficult area of investigation. In recent years, the tools of molecular biology have been applied to test a concept previously developed from physiological studies that glucose transport and phosphorylation represent key regulatory steps for glucose-stimulated insulin secretion. This article summarizes the recent molecular studies, deals with controversial issues that have arisen in the area, and highlights the role of defects in glucose transport and phosphorylation in certain forms of diabetes.
Duke Scholars
Published In
Diabetes Reviews
ISSN
1066-9442
Publication Date
January 1, 1996
Volume
4
Issue
2
Start / End Page
191 / 206
Citation
APA
Chicago
ICMJE
MLA
NLM
Newgard, C. B. (1996). Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells. Diabetes Reviews, 4(2), 191–206.
Newgard, C. B. “Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells.” Diabetes Reviews 4, no. 2 (January 1, 1996): 191–206.
Newgard CB. Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells. Diabetes Reviews. 1996 Jan 1;4(2):191–206.
Newgard, C. B. “Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells.” Diabetes Reviews, vol. 4, no. 2, Jan. 1996, pp. 191–206.
Newgard CB. Regulatory role of glucose transport and phosphorylation in pancreatic islet β-cells. Diabetes Reviews. 1996 Jan 1;4(2):191–206.
Published In
Diabetes Reviews
ISSN
1066-9442
Publication Date
January 1, 1996
Volume
4
Issue
2
Start / End Page
191 / 206