Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis.
Publication
, Journal Article
Steerman, RL; Snyderman, R; Leikin, SL; Colten, HR
Published in: Clin Exp Immunol
December 1971
A patient is presented who has recurrent infections associated with a cellular defect of PMN chemotaxis and phagocytosis, as well as a sex-linked form of congenital agammaglobulinaemia. The impairments of PMN function were demonstrated in vitro by an inability of the patient's PMNs to respond to chemotactic factors, by an inability of the PMNs to phagocytize S. aureus, and by abnormal NBT tests. These abnormalities were not corrected by the addition of normal serum or plasma to the patient's PMNs. No evidence was obtained for a plasma inhibitor of PMN function.
Duke Scholars
Published In
Clin Exp Immunol
ISSN
0009-9104
Publication Date
December 1971
Volume
9
Issue
6
Start / End Page
939 / 946
Location
England
Related Subject Headings
- Tetrazolium Salts
- Staphylococcus
- Skin
- Sex Chromosomes
- Recurrence
- Phagocytosis
- Phagocyte Bactericidal Dysfunction
- Male
- Leukocytes
- Infections
Citation
APA
Chicago
ICMJE
MLA
NLM
Steerman, R. L., Snyderman, R., Leikin, S. L., & Colten, H. R. (1971). Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. Clin Exp Immunol, 9(6), 939–946.
Steerman, R. L., R. Snyderman, S. L. Leikin, and H. R. Colten. “Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis.” Clin Exp Immunol 9, no. 6 (December 1971): 939–46.
Steerman RL, Snyderman R, Leikin SL, Colten HR. Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. Clin Exp Immunol. 1971 Dec;9(6):939–46.
Steerman, R. L., et al. “Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis.” Clin Exp Immunol, vol. 9, no. 6, Dec. 1971, pp. 939–46.
Steerman RL, Snyderman R, Leikin SL, Colten HR. Instrinsic defect of the polymorphonuclear leucocyte resulting in impaired chemotaxis and phagocytosis. Clin Exp Immunol. 1971 Dec;9(6):939–946.
Published In
Clin Exp Immunol
ISSN
0009-9104
Publication Date
December 1971
Volume
9
Issue
6
Start / End Page
939 / 946
Location
England
Related Subject Headings
- Tetrazolium Salts
- Staphylococcus
- Skin
- Sex Chromosomes
- Recurrence
- Phagocytosis
- Phagocyte Bactericidal Dysfunction
- Male
- Leukocytes
- Infections