Deep venous thrombosis and a circulating anticoagulant in systemic lupus erythematosus.
We describe deep venous thrombosis and a circulating anticoagulant in a male adolescent with systemic lupus erythematosus (SLE). The association of deep vein thrombosis with SLE in a pediatric patient has not, to our knowledge, been previously reported. The circulating anticoagulant was characterized as a lupus-type inhibitor. This was demonstrated by an abnormal partial thromboplastin time (PTT), the failure of the PTT to correct with the addition of an equal amount of normal plasma, and a positive tissue thromboplastin inhibitor test. Physicians should be aware that a circulating anticoagulant can be associated with SLE and that there may be a paradoxically increased incidence of thromboembolic phenomena in patients with this abnormality.
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- Thrombophlebitis
- Partial Thromboplastin Time
- Male
- Lupus Erythematosus, Systemic
- Humans
- Child
- Adult
- Adolescent
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Thrombophlebitis
- Partial Thromboplastin Time
- Male
- Lupus Erythematosus, Systemic
- Humans
- Child
- Adult
- Adolescent