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Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions.

Publication ,  Journal Article
Steffens, DC; Krishnan, KR
Published in: Biol Psychiatry
May 15, 1998

Neuroimaging is playing an increasing role in research of affective disorders, with investigators examining both volumetric changes of specific brain structures and vascular changes within white and gray matter. Recent studies have attempted to make clinical correlations between neuroimaging changes in unipolar and bipolar mood disorders. In this review, we focus particularly on those changes that are clinically meaningful. We conclude that there is enough evidence to begin to evaluate inclusion of neuroimaging findings in our mood disorder classification system. To this end, we propose two new mood disorder subtypes, vascular depression and vascular mania. Directions for future research in neuroimaging are then discussed.

Duke Scholars

Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

May 15, 1998

Volume

43

Issue

10

Start / End Page

705 / 712

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Psychiatry
  • Neurocognitive Disorders
  • Magnetic Resonance Imaging
  • Humans
  • Depressive Disorder
  • Cerebrovascular Disorders
  • Brain
  • Bipolar Disorder
  • 52 Psychology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Steffens, D. C., & Krishnan, K. R. (1998). Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions. Biol Psychiatry, 43(10), 705–712. https://doi.org/10.1016/s0006-3223(98)00084-5
Steffens, D. C., and K. R. Krishnan. “Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions.Biol Psychiatry 43, no. 10 (May 15, 1998): 705–12. https://doi.org/10.1016/s0006-3223(98)00084-5.
Steffens, D. C., and K. R. Krishnan. “Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions.Biol Psychiatry, vol. 43, no. 10, May 1998, pp. 705–12. Pubmed, doi:10.1016/s0006-3223(98)00084-5.
Journal cover image

Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

May 15, 1998

Volume

43

Issue

10

Start / End Page

705 / 712

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Psychiatry
  • Neurocognitive Disorders
  • Magnetic Resonance Imaging
  • Humans
  • Depressive Disorder
  • Cerebrovascular Disorders
  • Brain
  • Bipolar Disorder
  • 52 Psychology