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Considerations in fractionated proton radiation therapy: clinical potential and results.

Publication ,  Journal Article
Austin-Seymour, M; Urie, M; Munzenrider, J; Willett, C; Goitein, M; Verhey, L; Gentry, R; McNulty, P; Koehler, A; Suit, H
Published in: Radiother Oncol
January 1990
Published version (DOI) Link to item

Protons have a finite range in tissue and can provide a better concentration of radiation dose in the tumor than conventional X-rays in certain situations. The development of optimized treatment plans for X-rays and protons followed by a comparative evaluation is one method of selecting tumor sites best suited for proton treatment. The preliminary results of comparative treatment planning for base of skull tumors and carcinoma of the prostate are discussed. These comparisons suggest a clinical gain for proton treatment of tumors in these locations. The clinical experience with fractionated proton treatment of several tumor sites is also discussed. The results of high dose proton treatment of chordomas and low grade chondrosarcomas of the base of skull is particularly promising: an actuarial 5-year local control of 78% has been obtained in 50 patients followed for a minimum of 22 months.

Duke Scholars

Christopher G. Willett
Author Christopher G. Willett Radiation Oncology

Published In

Radiother Oncol

DOI

10.1016/0167-8140(90)90046-y

ISSN

0167-8140

Publication Date

January 1990

Volume

17

Issue

1

Start / End Page

29 / 35

Location

Ireland

Related Subject Headings

  • Soft Tissue Neoplasms
  • Skull Neoplasms
  • Sarcoma
  • Randomized Controlled Trials as Topic
  • Radiotherapy, High-Energy
  • Radiotherapy Planning, Computer-Assisted
  • Protons
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
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Austin-Seymour, M., Urie, M., Munzenrider, J., Willett, C., Goitein, M., Verhey, L., … Suit, H. (1990). Considerations in fractionated proton radiation therapy: clinical potential and results. Radiother Oncol, 17(1), 29–35. https://doi.org/10.1016/0167-8140(90)90046-y
Austin-Seymour, M., M. Urie, J. Munzenrider, C. Willett, M. Goitein, L. Verhey, R. Gentry, P. McNulty, A. Koehler, and H. Suit. “Considerations in fractionated proton radiation therapy: clinical potential and results.” Radiother Oncol 17, no. 1 (January 1990): 29–35. https://doi.org/10.1016/0167-8140(90)90046-y.
Austin-Seymour M, Urie M, Munzenrider J, Willett C, Goitein M, Verhey L, et al. Considerations in fractionated proton radiation therapy: clinical potential and results. Radiother Oncol. 1990 Jan;17(1):29–35.
Austin-Seymour, M., et al. “Considerations in fractionated proton radiation therapy: clinical potential and results.” Radiother Oncol, vol. 17, no. 1, Jan. 1990, pp. 29–35. Pubmed, doi:10.1016/0167-8140(90)90046-y.
Austin-Seymour M, Urie M, Munzenrider J, Willett C, Goitein M, Verhey L, Gentry R, McNulty P, Koehler A, Suit H. Considerations in fractionated proton radiation therapy: clinical potential and results. Radiother Oncol. 1990 Jan;17(1):29–35.
Journal cover image

Published In

Radiother Oncol

DOI

10.1016/0167-8140(90)90046-y

ISSN

0167-8140

Publication Date

January 1990

Volume

17

Issue

1

Start / End Page

29 / 35

Location

Ireland

Related Subject Headings

  • Soft Tissue Neoplasms
  • Skull Neoplasms
  • Sarcoma
  • Randomized Controlled Trials as Topic
  • Radiotherapy, High-Energy
  • Radiotherapy Planning, Computer-Assisted
  • Protons
  • Prostatic Neoplasms
  • Oncology & Carcinogenesis
  • Male