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Control for confounding in case-control studies using the stratification score, a retrospective balancing score.

Publication ,  Journal Article
Allen, AS; Satten, GA
Published in: Am J Epidemiol
April 1, 2011

The stratification score for a case-control study is the probability of disease modeled as a function of potential confounders. The authors show that the stratification score is a retrospective balancing score and thus plays a similar role in case-control studies as the propensity score plays in prospective studies. The authors further show how standardization using the stratification score can be used to compare the distributions of exposures that would be found among case and control participants if both groups had the same distribution of confounding covariables. The authors illustrate these results using data from a genome-wide association study, the GAIN (Genetic Association Information Network) study of schizophrenia among African Americans (2006-2008).

Duke Scholars

Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

April 1, 2011

Volume

173

Issue

7

Start / End Page

752 / 760

Location

United States

Related Subject Headings

  • Schizophrenia
  • Retrospective Studies
  • Propensity Score
  • Probability
  • Models, Statistical
  • Humans
  • Genome-Wide Association Study
  • Epidemiology
  • Epidemiologic Research Design
  • Confounding Factors, Epidemiologic
 

Citation

APA
Chicago
ICMJE
MLA
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Allen, A. S., & Satten, G. A. (2011). Control for confounding in case-control studies using the stratification score, a retrospective balancing score. Am J Epidemiol, 173(7), 752–760. https://doi.org/10.1093/aje/kwq406
Allen, Andrew S., and Glen A. Satten. “Control for confounding in case-control studies using the stratification score, a retrospective balancing score.Am J Epidemiol 173, no. 7 (April 1, 2011): 752–60. https://doi.org/10.1093/aje/kwq406.
Allen, Andrew S., and Glen A. Satten. “Control for confounding in case-control studies using the stratification score, a retrospective balancing score.Am J Epidemiol, vol. 173, no. 7, Apr. 2011, pp. 752–60. Pubmed, doi:10.1093/aje/kwq406.
Journal cover image

Published In

Am J Epidemiol

DOI

EISSN

1476-6256

Publication Date

April 1, 2011

Volume

173

Issue

7

Start / End Page

752 / 760

Location

United States

Related Subject Headings

  • Schizophrenia
  • Retrospective Studies
  • Propensity Score
  • Probability
  • Models, Statistical
  • Humans
  • Genome-Wide Association Study
  • Epidemiology
  • Epidemiologic Research Design
  • Confounding Factors, Epidemiologic