Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus.
Publication
, Journal Article
Stabler, T; Kenjale, A; Ham, K; Jelesoff, N; Allen, J
Published in: Ann N Y Acad Sci
August 2010
Nitric oxide (NO) bioavailability is crucial for normal vascular endothelial function and health. Recent studies have demonstrated an endocrine role for NO equivalents that may be transported in the blood to peripheral tissue beds, where under hypoxic conditions they can liberate NO and cause vasodilation. Exercise training improves endothelial function but its effect on NO bioavailability in peripheral tissues during acute exercise stress in CVD is unclear. This paper will present evidence and discuss possible mechanisms by which NO delivery to peripheral tissues may be dysfunctional in diabetic subjects.
Duke Scholars
Published In
Ann N Y Acad Sci
DOI
EISSN
1749-6632
Publication Date
August 2010
Volume
1203
Start / End Page
101 / 106
Location
United States
Related Subject Headings
- Vasodilation
- Nitric Oxide
- Humans
- General Science & Technology
- Endothelium, Vascular
- Diabetes Mellitus
- Biological Transport
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Stabler, T., Kenjale, A., Ham, K., Jelesoff, N., & Allen, J. (2010). Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus. Ann N Y Acad Sci, 1203, 101–106. https://doi.org/10.1111/j.1749-6632.2010.05599.x
Stabler, Thomas, Aarti Kenjale, Katherine Ham, Nicole Jelesoff, and Jason Allen. “Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus.” Ann N Y Acad Sci 1203 (August 2010): 101–6. https://doi.org/10.1111/j.1749-6632.2010.05599.x.
Stabler T, Kenjale A, Ham K, Jelesoff N, Allen J. Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus. Ann N Y Acad Sci. 2010 Aug;1203:101–6.
Stabler, Thomas, et al. “Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus.” Ann N Y Acad Sci, vol. 1203, Aug. 2010, pp. 101–06. Pubmed, doi:10.1111/j.1749-6632.2010.05599.x.
Stabler T, Kenjale A, Ham K, Jelesoff N, Allen J. Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitus. Ann N Y Acad Sci. 2010 Aug;1203:101–106.
Published In
Ann N Y Acad Sci
DOI
EISSN
1749-6632
Publication Date
August 2010
Volume
1203
Start / End Page
101 / 106
Location
United States
Related Subject Headings
- Vasodilation
- Nitric Oxide
- Humans
- General Science & Technology
- Endothelium, Vascular
- Diabetes Mellitus
- Biological Transport
- Animals