Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy.
Publication
, Journal Article
Becker, RC; Oney, S; Becker, KCD; Rusconi, CP; Sullenger, B
Published in: Hamostaseologie
December 2007
The translation of fundamental science-based constructs to the preemptive identification and optimal management of individuals with or those at risk for thrombotic disorders of the cardiovascular system has taken a step closer to being realized with the development of molecular technologies that include nucleic acid aptamers and their complimentary oligonucleotide antidotes. Herein, we summarize our experience with factor IX and von Willebrand factor aptamers, and introduce the era of antithrombotic pharmacobiologic therapy.
Duke Scholars
Published In
Hamostaseologie
ISSN
0720-9355
Publication Date
December 2007
Volume
27
Issue
5
Start / End Page
378 / 382
Location
Germany
Related Subject Headings
- Thrombolytic Therapy
- Reproducibility of Results
- Randomized Controlled Trials as Topic
- Humans
- Fibrinolytic Agents
- Clinical Trials as Topic
- Cardiovascular System & Hematology
- Blood Coagulation Factors
Citation
APA
Chicago
ICMJE
MLA
NLM
Becker, R. C., Oney, S., Becker, K. C. D., Rusconi, C. P., & Sullenger, B. (2007). Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy. Hamostaseologie, 27(5), 378–382.
Becker, R. C., S. Oney, K. C. D. Becker, C. P. Rusconi, and B. Sullenger. “Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy.” Hamostaseologie 27, no. 5 (December 2007): 378–82.
Becker RC, Oney S, Becker KCD, Rusconi CP, Sullenger B. Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy. Hamostaseologie. 2007 Dec;27(5):378–82.
Becker, R. C., et al. “Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy.” Hamostaseologie, vol. 27, no. 5, Dec. 2007, pp. 378–82.
Becker RC, Oney S, Becker KCD, Rusconi CP, Sullenger B. Nucleic acid aptamers and their complimentary antidotes. Entering an era of antithrombotic pharmacobiologic therapy. Hamostaseologie. 2007 Dec;27(5):378–382.
Published In
Hamostaseologie
ISSN
0720-9355
Publication Date
December 2007
Volume
27
Issue
5
Start / End Page
378 / 382
Location
Germany
Related Subject Headings
- Thrombolytic Therapy
- Reproducibility of Results
- Randomized Controlled Trials as Topic
- Humans
- Fibrinolytic Agents
- Clinical Trials as Topic
- Cardiovascular System & Hematology
- Blood Coagulation Factors