Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.
Publication
, Journal Article
González, F; Swales, L; Bejsovec, A; Skaer, H; Martinez Arias, A
Published in: Mechanisms of development
August 1991
The segment polarity gene wingless encodes a cysteine rich protein which is essential for pattern formation in Drosophila. Using polyclonal antibodies against the product of the wingless gene, we demonstrate that this protein is secreted in the embryo and that it is taken up by neighbouring cells. The protein can be found two or three cell diameters away from the cells in which it is synthesized. We discuss the possible mechanisms which are responsible for this spatial distribution and its regulation during embryogenesis.
Duke Scholars
Published In
Mechanisms of development
DOI
EISSN
1872-6356
ISSN
0925-4773
Publication Date
August 1991
Volume
35
Issue
1
Start / End Page
43 / 54
Related Subject Headings
- RNA
- Proteins
- Immunohistochemistry
- Gene Expression Regulation
- Epidermis
- Embryo, Nonmammalian
- Drosophila
- Developmental Biology
- Biological Transport
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
González, F., Swales, L., Bejsovec, A., Skaer, H., & Martinez Arias, A. (1991). Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mechanisms of Development, 35(1), 43–54. https://doi.org/10.1016/0925-4773(91)90040-d
González, F., L. Swales, A. Bejsovec, H. Skaer, and A. Martinez Arias. “Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.” Mechanisms of Development 35, no. 1 (August 1991): 43–54. https://doi.org/10.1016/0925-4773(91)90040-d.
González F, Swales L, Bejsovec A, Skaer H, Martinez Arias A. Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mechanisms of development. 1991 Aug;35(1):43–54.
González, F., et al. “Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.” Mechanisms of Development, vol. 35, no. 1, Aug. 1991, pp. 43–54. Epmc, doi:10.1016/0925-4773(91)90040-d.
González F, Swales L, Bejsovec A, Skaer H, Martinez Arias A. Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. Mechanisms of development. 1991 Aug;35(1):43–54.
Published In
Mechanisms of development
DOI
EISSN
1872-6356
ISSN
0925-4773
Publication Date
August 1991
Volume
35
Issue
1
Start / End Page
43 / 54
Related Subject Headings
- RNA
- Proteins
- Immunohistochemistry
- Gene Expression Regulation
- Epidermis
- Embryo, Nonmammalian
- Drosophila
- Developmental Biology
- Biological Transport
- Animals