Pharmacotherapy of bipolar disorder in old age: review and recommendations.
Publication
, Journal Article
Young, RC; Gyulai, L; Mulsant, BH; Flint, A; Beyer, JL; Shulman, KI; Reynolds, CF
Published in: Am J Geriatr Psychiatry
2004
The authors reviewed the evidence-base for pharmacological treatment of mania and bipolar (BP) depression in late life. Treatment benefits and side effects may be modified by age-associated factors, such as neurocognitive impairments. Lithium and divalproex have most often been studied in elderly patients, and both may be efficacious in acute treatment of mania, but there are no controlled efficacy or effectiveness trials. The role of atypical antipsychotic agents remains to be clarified. Similarly, there are no systematic studies of the treatment of BP depression in elderly patients. The authors make suggestions for management and delineate priorities for research.
Duke Scholars
Published In
Am J Geriatr Psychiatry
DOI
ISSN
1064-7481
Publication Date
2004
Volume
12
Issue
4
Start / End Page
342 / 357
Location
England
Related Subject Headings
- Treatment Outcome
- Lithium Carbonate
- Humans
- Geriatrics
- Drug Administration Schedule
- Bipolar Disorder
- Antipsychotic Agents
- Aged
- 5203 Clinical and health psychology
- 4203 Health services and systems
Citation
APA
Chicago
ICMJE
MLA
NLM
Young, R. C., Gyulai, L., Mulsant, B. H., Flint, A., Beyer, J. L., Shulman, K. I., & Reynolds, C. F. (2004). Pharmacotherapy of bipolar disorder in old age: review and recommendations. Am J Geriatr Psychiatry, 12(4), 342–357. https://doi.org/10.1176/appi.ajgp.12.4.342
Young, Robert C., Laszlo Gyulai, Benoit H. Mulsant, Alastair Flint, John L. Beyer, Kenneth I. Shulman, and Charles F. Reynolds. “Pharmacotherapy of bipolar disorder in old age: review and recommendations.” Am J Geriatr Psychiatry 12, no. 4 (2004): 342–57. https://doi.org/10.1176/appi.ajgp.12.4.342.
Young RC, Gyulai L, Mulsant BH, Flint A, Beyer JL, Shulman KI, et al. Pharmacotherapy of bipolar disorder in old age: review and recommendations. Am J Geriatr Psychiatry. 2004;12(4):342–57.
Young, Robert C., et al. “Pharmacotherapy of bipolar disorder in old age: review and recommendations.” Am J Geriatr Psychiatry, vol. 12, no. 4, 2004, pp. 342–57. Pubmed, doi:10.1176/appi.ajgp.12.4.342.
Young RC, Gyulai L, Mulsant BH, Flint A, Beyer JL, Shulman KI, Reynolds CF. Pharmacotherapy of bipolar disorder in old age: review and recommendations. Am J Geriatr Psychiatry. 2004;12(4):342–357.
Published In
Am J Geriatr Psychiatry
DOI
ISSN
1064-7481
Publication Date
2004
Volume
12
Issue
4
Start / End Page
342 / 357
Location
England
Related Subject Headings
- Treatment Outcome
- Lithium Carbonate
- Humans
- Geriatrics
- Drug Administration Schedule
- Bipolar Disorder
- Antipsychotic Agents
- Aged
- 5203 Clinical and health psychology
- 4203 Health services and systems