Anticholinergic effects in frogs in a Morris water maze analog.
Publication
, Journal Article
Bilbo, SD; Day, LB; Wilczynski, W
Published in: Physiology & behavior
May 2000
We determined the effect of two doses of the centrally acting anticholinergic drug, atropine sulfate (AS), on the performance of female Northern Leopard frogs (Rana pipiens) in a visual cue analog of the Morris water task. Untreated frogs learned the visually cued task, while frogs treated with 150 mg/kg AS were significantly slower than controls in learning to escape warm water by finding a visible platform, and there was a dose-dependent response, with frogs treated with 50 mg/kg AS performing midway between the higher dose and control frogs. These results suggest that the general role of the cholinergic system in learning is important in amphibians, and that this role is evolutionarily conserved across vertebrate species.
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Published In
Physiology & behavior
DOI
EISSN
1873-507X
ISSN
0031-9384
Publication Date
May 2000
Volume
69
Issue
3
Start / End Page
351 / 357
Related Subject Headings
- Swimming
- Rana pipiens
- Muscarinic Antagonists
- Maze Learning
- Female
- Cues
- Cholinergic Antagonists
- Behavioral Science & Comparative Psychology
- Atropine
- Animals
Citation
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Chicago
ICMJE
MLA
NLM
Bilbo, S. D., Day, L. B., & Wilczynski, W. (2000). Anticholinergic effects in frogs in a Morris water maze analog. Physiology & Behavior, 69(3), 351–357. https://doi.org/10.1016/s0031-9384(99)00251-6
Bilbo, S. D., L. B. Day, and W. Wilczynski. “Anticholinergic effects in frogs in a Morris water maze analog.” Physiology & Behavior 69, no. 3 (May 2000): 351–57. https://doi.org/10.1016/s0031-9384(99)00251-6.
Bilbo SD, Day LB, Wilczynski W. Anticholinergic effects in frogs in a Morris water maze analog. Physiology & behavior. 2000 May;69(3):351–7.
Bilbo, S. D., et al. “Anticholinergic effects in frogs in a Morris water maze analog.” Physiology & Behavior, vol. 69, no. 3, May 2000, pp. 351–57. Epmc, doi:10.1016/s0031-9384(99)00251-6.
Bilbo SD, Day LB, Wilczynski W. Anticholinergic effects in frogs in a Morris water maze analog. Physiology & behavior. 2000 May;69(3):351–357.
Published In
Physiology & behavior
DOI
EISSN
1873-507X
ISSN
0031-9384
Publication Date
May 2000
Volume
69
Issue
3
Start / End Page
351 / 357
Related Subject Headings
- Swimming
- Rana pipiens
- Muscarinic Antagonists
- Maze Learning
- Female
- Cues
- Cholinergic Antagonists
- Behavioral Science & Comparative Psychology
- Atropine
- Animals