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Thrombolytic therapy: overview of clinical trials

Publication ,  Journal Article
Ohman, EM; Califf, RM
Published in: Coronary Artery Disease
January 1, 1990

With over 50,000 patients studied in various clinical trials, administration of thrombolytic therapy in acute myocardial infarction is probably the most thoroughly studied pharmacologic intervention in medical history. Since the concept wwas explored that thrombotic occlusion of a coronary artery was the culprit during acute myocardial infarction [1] and that agents that induced a fibrinolytic state could dissolve this clot (Chazov et al., Ter Arkh 1976, 48:8-19), a substantial experience has been gained concerning the impact of different thrombolytic agents on patency of the infarct-related artery, left ventricular function, and mortality.

Duke Scholars

Published In

Coronary Artery Disease

DOI

ISSN

0954-6928

Publication Date

January 1, 1990

Volume

1

Issue

1

Start / End Page

23 / 33

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

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Ohman, E. M., & Califf, R. M. (1990). Thrombolytic therapy: overview of clinical trials. Coronary Artery Disease, 1(1), 23–33. https://doi.org/10.1097/00019501-199001000-00005
Ohman, E. M., and R. M. Califf. “Thrombolytic therapy: overview of clinical trials.” Coronary Artery Disease 1, no. 1 (January 1, 1990): 23–33. https://doi.org/10.1097/00019501-199001000-00005.
Ohman EM, Califf RM. Thrombolytic therapy: overview of clinical trials. Coronary Artery Disease. 1990 Jan 1;1(1):23–33.
Ohman, E. M., and R. M. Califf. “Thrombolytic therapy: overview of clinical trials.” Coronary Artery Disease, vol. 1, no. 1, Jan. 1990, pp. 23–33. Scopus, doi:10.1097/00019501-199001000-00005.
Ohman EM, Califf RM. Thrombolytic therapy: overview of clinical trials. Coronary Artery Disease. 1990 Jan 1;1(1):23–33.

Published In

Coronary Artery Disease

DOI

ISSN

0954-6928

Publication Date

January 1, 1990

Volume

1

Issue

1

Start / End Page

23 / 33

Related Subject Headings

  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences