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Hedgehog signaling: is Smo a G protein-coupled receptor?

Publication ,  Journal Article
Philipp, M; Caron, MG
Published in: Curr Biol
February 10, 2009

The Hedgehog signal transducer Smoothened is structurally similar to G protein-coupled receptors. Now there is direct evidence that Smoothened relies on heterotrimeric G proteins in order to transduce the Hedgehog signal.

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Published In

Curr Biol

DOI

EISSN

1879-0445

Publication Date

February 10, 2009

Volume

19

Issue

3

Start / End Page

R125 / R127

Location

England

Related Subject Headings

  • Smoothened Receptor
  • Signal Transduction
  • Receptors, G-Protein-Coupled
  • Models, Biological
  • Hedgehog Proteins
  • Drosophila Proteins
  • Developmental Biology
  • 52 Psychology
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
 

Citation

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Philipp, M., & Caron, M. G. (2009). Hedgehog signaling: is Smo a G protein-coupled receptor? Curr Biol, 19(3), R125–R127. https://doi.org/10.1016/j.cub.2008.12.010
Philipp, Melanie, and Marc G. Caron. “Hedgehog signaling: is Smo a G protein-coupled receptor?Curr Biol 19, no. 3 (February 10, 2009): R125–27. https://doi.org/10.1016/j.cub.2008.12.010.
Philipp M, Caron MG. Hedgehog signaling: is Smo a G protein-coupled receptor? Curr Biol. 2009 Feb 10;19(3):R125–7.
Philipp, Melanie, and Marc G. Caron. “Hedgehog signaling: is Smo a G protein-coupled receptor?Curr Biol, vol. 19, no. 3, Feb. 2009, pp. R125–27. Pubmed, doi:10.1016/j.cub.2008.12.010.
Philipp M, Caron MG. Hedgehog signaling: is Smo a G protein-coupled receptor? Curr Biol. 2009 Feb 10;19(3):R125–R127.
Journal cover image

Published In

Curr Biol

DOI

EISSN

1879-0445

Publication Date

February 10, 2009

Volume

19

Issue

3

Start / End Page

R125 / R127

Location

England

Related Subject Headings

  • Smoothened Receptor
  • Signal Transduction
  • Receptors, G-Protein-Coupled
  • Models, Biological
  • Hedgehog Proteins
  • Drosophila Proteins
  • Developmental Biology
  • 52 Psychology
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences