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Control of GVHD: It's in our DNA!

Publication ,  Journal Article
Chao, N
Published in: Blood
February 2, 2012

Selective depletion of the alloreactiveT cells causing graft-versus-host disease (GVHD) without loss of the graft-versus-leukemia (GVL) effect is the holy grail of hematopoietic cell transplantation (HCT). In this issue of Blood, He et al demonstrate that inhibition of histone methylation leads to selective apoptosis of the alloreactive effector cells.1 Moreover, they demonstrate that this inhibition of histone methylation remarkably stops ongoing GVHD.

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Published In

Blood

DOI

EISSN

1528-0020

ISSN

0006-4971

Publication Date

February 2, 2012

Volume

119

Issue

5

Start / End Page

1102 / 1103

Related Subject Headings

  • Immunology
  • 3213 Paediatrics
  • 3201 Cardiovascular medicine and haematology
  • 3101 Biochemistry and cell biology
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chao, N. (2012). Control of GVHD: It's in our DNA!. Blood, 119(5), 1102–1103. https://doi.org/10.1182/blood-2011-12-395905
Chao, N. “Control of GVHD: It's in our DNA!.” Blood 119, no. 5 (February 2, 2012): 1102–3. https://doi.org/10.1182/blood-2011-12-395905.
Chao N. Control of GVHD: It's in our DNA!. Blood. 2012 Feb 2;119(5):1102–3.
Chao, N. “Control of GVHD: It's in our DNA!.” Blood, vol. 119, no. 5, Feb. 2012, pp. 1102–03. Scopus, doi:10.1182/blood-2011-12-395905.
Chao N. Control of GVHD: It's in our DNA!. Blood. 2012 Feb 2;119(5):1102–1103.

Published In

Blood

DOI

EISSN

1528-0020

ISSN

0006-4971

Publication Date

February 2, 2012

Volume

119

Issue

5

Start / End Page

1102 / 1103

Related Subject Headings

  • Immunology
  • 3213 Paediatrics
  • 3201 Cardiovascular medicine and haematology
  • 3101 Biochemistry and cell biology
  • 1114 Paediatrics and Reproductive Medicine
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology