Glucose challenge test screening for prediabetes and undiagnosed diabetes.
AIMS/HYPOTHESIS: Diabetes prevention and care are limited by lack of screening. We hypothesised that screening could be done with a strategy similar to that used near-universally for gestational diabetes, i.e. a 50 g oral glucose challenge test (GCT) performed at any time of day, regardless of meal status, with one 1 h sample. METHODS: At a first visit, participants had random plasma and capillary glucose measured, followed by the GCT with plasma and capillary glucose (GCTplasma and GCTcap, respectively). At a second visit, participants had HbA(1c) measured and a diagnostic 75 g OGTT. RESULTS: The 1,573 participants had mean age of 48 years, BMI 30.3 kg/m(2) and 58% were women and 58% were black. Diabetes (defined by WHO) was present in 4.6% and prediabetes (defined as impaired glucose tolerance [2 h glucose 7.8-11.1 (140-199 mg/dl) with fasting glucose
Duke Scholars
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- Young Adult
- White People
- Pregnancy
- Prediabetic State
- Middle Aged
- Mass Screening
- Male
- Humans
- Glycated Hemoglobin
- Glucose Tolerance Test
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Young Adult
- White People
- Pregnancy
- Prediabetic State
- Middle Aged
- Mass Screening
- Male
- Humans
- Glycated Hemoglobin
- Glucose Tolerance Test