HIV entry inhibitors: progress in development and application.
Publication
, Journal Article
Lai, W-H; Huang, L; Chen, C-H
Published in: Yao Xue Xue Bao
February 2010
This review discusses recent progress in the development of anti-HIV agents, with emphasis on small molecule HIV-1 entry inhibitors. The entry inhibitors primarily target HIV-1 envelope glycoproteins or the cellular receptors, CD4 and chemokine receptors. Two of the entry inhibitors, enfuvirtide and maraviroc, have been approved by the US FDA for AIDS therapy. The drug resistance associated with some of the entry inhibitors will also be discussed.
Duke Scholars
Published In
Yao Xue Xue Bao
ISSN
0513-4870
Publication Date
February 2010
Volume
45
Issue
2
Start / End Page
131 / 140
Location
China
Related Subject Headings
- Triazoles
- Receptors, Chemokine
- Receptors, CXCR4
- Receptors, CCR5
- Pharmacology & Pharmacy
- Peptide Fragments
- Molecular Structure
- Maraviroc
- Humans
- HIV-1
Citation
APA
Chicago
ICMJE
MLA
NLM
Lai, W.-H., Huang, L., & Chen, C.-H. (2010). HIV entry inhibitors: progress in development and application. Yao Xue Xue Bao, 45(2), 131–140.
Lai, Wei-hong, Li Huang, and Chin-ho Chen. “HIV entry inhibitors: progress in development and application.” Yao Xue Xue Bao 45, no. 2 (February 2010): 131–40.
Lai W-H, Huang L, Chen C-H. HIV entry inhibitors: progress in development and application. Yao Xue Xue Bao. 2010 Feb;45(2):131–40.
Lai, Wei-hong, et al. “HIV entry inhibitors: progress in development and application.” Yao Xue Xue Bao, vol. 45, no. 2, Feb. 2010, pp. 131–40.
Lai W-H, Huang L, Chen C-H. HIV entry inhibitors: progress in development and application. Yao Xue Xue Bao. 2010 Feb;45(2):131–140.
Published In
Yao Xue Xue Bao
ISSN
0513-4870
Publication Date
February 2010
Volume
45
Issue
2
Start / End Page
131 / 140
Location
China
Related Subject Headings
- Triazoles
- Receptors, Chemokine
- Receptors, CXCR4
- Receptors, CCR5
- Pharmacology & Pharmacy
- Peptide Fragments
- Molecular Structure
- Maraviroc
- Humans
- HIV-1