Medical genetics: a marker for Stevens-Johnson syndrome.
Publication
, Journal Article
Chung, WH; Hung, SI; Hong, HS; Hsih, MS; Yang, LC; Ho, HC; Wu, JY; Chen, YT
Published in: Nature
2004
Stevens-Johnson syndrome and the related disease toxic epidermal necrolysis are life-threatening reactions of the skin to particular types of medication. Here we show that there is a strong association in Han Chinese between a genetic marker, the human leukocyte antigen HLA-B*1502, and Stevens-Johnson syndrome induced by carbamazepine, a drug commonly prescribed for the treatment of seizures. It should be possible to exploit this association in a highly reliable test to predict severe adverse reaction, as well as for investigation of the pathogenesis of Stevens-Johnson syndrome.
Duke Scholars
Published In
Nature
Publication Date
2004
Volume
428
Issue
6982
Start / End Page
486-
Related Subject Headings
- General Science & Technology
Citation
APA
Chicago
ICMJE
MLA
NLM
Chung, W. H., Hung, S. I., Hong, H. S., Hsih, M. S., Yang, L. C., Ho, H. C., … Chen, Y. T. (2004). Medical genetics: a marker for Stevens-Johnson syndrome. Nature, 428(6982), 486-.
Chung, W. H., S. I. Hung, H. S. Hong, M. S. Hsih, L. C. Yang, H. C. Ho, J. Y. Wu, and Y. T. Chen. “Medical genetics: a marker for Stevens-Johnson syndrome.” Nature 428, no. 6982 (2004): 486-.
Chung WH, Hung SI, Hong HS, Hsih MS, Yang LC, Ho HC, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature. 2004;428(6982):486-.
Chung, W. H., et al. “Medical genetics: a marker for Stevens-Johnson syndrome.” Nature, vol. 428, no. 6982, 2004, pp. 486-.
Chung WH, Hung SI, Hong HS, Hsih MS, Yang LC, Ho HC, Wu JY, Chen YT. Medical genetics: a marker for Stevens-Johnson syndrome. Nature. 2004;428(6982):486-.
Published In
Nature
Publication Date
2004
Volume
428
Issue
6982
Start / End Page
486-
Related Subject Headings
- General Science & Technology