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Hyperammonemia in the ICU.

Publication ,  Journal Article
Clay, AS; Hainline, BE
Published in: Chest
October 2007

Patients experiencing acute elevations of ammonia present to the ICU with encephalopathy, which may progress quickly to cerebral herniation. Patient survival requires immediate treatment of intracerebral hypertension and the reduction of ammonia levels. When hyperammonemia is not thought to be the result of liver failure, treatment for an occult disorder of metabolism must begin prior to the confirmation of an etiology. This article reviews ammonia metabolism, the effects of ammonia on the brain, the causes of hyperammonemia, and the diagnosis of inborn errors of metabolism in adult patients.

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Published In

Chest

DOI

ISSN

0012-3692

Publication Date

October 2007

Volume

132

Issue

4

Start / End Page

1368 / 1378

Location

United States

Related Subject Headings

  • Urea
  • Respiratory System
  • Muscle, Skeletal
  • Metabolism, Inborn Errors
  • Liver Function Tests
  • Liver Failure, Acute
  • Liver
  • Intensive Care Units
  • Hypothermia, Induced
  • Hyperammonemia
 

Citation

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Clay, A. S., & Hainline, B. E. (2007). Hyperammonemia in the ICU. Chest, 132(4), 1368–1378. https://doi.org/10.1378/chest.06-2940
Clay, Alison S., and Bryan E. Hainline. “Hyperammonemia in the ICU.Chest 132, no. 4 (October 2007): 1368–78. https://doi.org/10.1378/chest.06-2940.
Clay AS, Hainline BE. Hyperammonemia in the ICU. Chest. 2007 Oct;132(4):1368–78.
Clay, Alison S., and Bryan E. Hainline. “Hyperammonemia in the ICU.Chest, vol. 132, no. 4, Oct. 2007, pp. 1368–78. Pubmed, doi:10.1378/chest.06-2940.
Clay AS, Hainline BE. Hyperammonemia in the ICU. Chest. 2007 Oct;132(4):1368–1378.
Journal cover image

Published In

Chest

DOI

ISSN

0012-3692

Publication Date

October 2007

Volume

132

Issue

4

Start / End Page

1368 / 1378

Location

United States

Related Subject Headings

  • Urea
  • Respiratory System
  • Muscle, Skeletal
  • Metabolism, Inborn Errors
  • Liver Function Tests
  • Liver Failure, Acute
  • Liver
  • Intensive Care Units
  • Hypothermia, Induced
  • Hyperammonemia