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Personality and inflammation: the protective effect of openness to experience.

Publication ,  Journal Article
Jonassaint, CR; Boyle, SH; Kuhn, CM; Siegler, IC; Copeland, WE; Williams, R
Published in: Ethn Dis
2010

BACKGROUND: Prior research found reduced mortality in coronary heart patients with higher scores on the Openness to Experience domain and its facets. Decreased C-reactive protein level (CRP) levels may be one mechanism by which higher Openness to Experience leads to decreased mortality. Thus, the current study aimed to test the association between the Openness to Experience domain and its facets, as assessed by the NEO Personality Inventory-Revised, and CRP in a sample of 165 healthy Black and White, male and female community volunteers. METHODS: Blood samples were taken before and after a 40-minute mental stress protocol. BMI and education were significant predictors of CRP and, in addition to age, were included as covariates in all analyses. Race and sex were tested as possible moderating variables. RESULTS: In a mixed effects model the main effect of time (pre/post-stress), Openness to Experience (O) and their interaction were not significant predictors of CRP. However, results showed a significant race x O effect on CRP (P=.03). In Blacks, higher Openness to Experience domain (r=-.41, P<.01), aesthetics facet (r=-.30, P=.01), feelings facet (r= -.41, P<.01), and ideas facet (r=-.38, P<.01) scores were associated with lower mean CRP levels. In contrast, among White participants, neither the Openness to Experience domain nor its related facets were associated with CRP. DISCUSSION: The Openness to Experience domain and its facets may be associated with markers of the inflammatory process among Blacks but not Whites.

Duke Scholars

Published In

Ethn Dis

ISSN

1049-510X

Publication Date

2010

Volume

20

Issue

1

Start / End Page

11 / 14

Location

United States

Related Subject Headings

  • White People
  • Stress, Psychological
  • Public Health
  • Personality
  • Male
  • Inflammation
  • Humans
  • Female
  • C-Reactive Protein
  • Black or African American
 

Citation

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Jonassaint, C. R., Boyle, S. H., Kuhn, C. M., Siegler, I. C., Copeland, W. E., & Williams, R. (2010). Personality and inflammation: the protective effect of openness to experience. Ethn Dis, 20(1), 11–14.
Jonassaint, Charles R., Stephen H. Boyle, Cynthia M. Kuhn, Ilene C. Siegler, William E. Copeland, and Redford Williams. “Personality and inflammation: the protective effect of openness to experience.Ethn Dis 20, no. 1 (2010): 11–14.
Jonassaint CR, Boyle SH, Kuhn CM, Siegler IC, Copeland WE, Williams R. Personality and inflammation: the protective effect of openness to experience. Ethn Dis. 2010;20(1):11–4.
Jonassaint, Charles R., et al. “Personality and inflammation: the protective effect of openness to experience.Ethn Dis, vol. 20, no. 1, 2010, pp. 11–14.
Jonassaint CR, Boyle SH, Kuhn CM, Siegler IC, Copeland WE, Williams R. Personality and inflammation: the protective effect of openness to experience. Ethn Dis. 2010;20(1):11–14.

Published In

Ethn Dis

ISSN

1049-510X

Publication Date

2010

Volume

20

Issue

1

Start / End Page

11 / 14

Location

United States

Related Subject Headings

  • White People
  • Stress, Psychological
  • Public Health
  • Personality
  • Male
  • Inflammation
  • Humans
  • Female
  • C-Reactive Protein
  • Black or African American