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Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm

Publication ,  Journal Article
Dhungana, S; Crumbliss, AL
Published in: Chemtracts
August 6, 2001

The siderophore-mediated iron transport in A. hydrophila was found to occur by means of a siderophore transport system with a very low specificity. At least two groups of transport systems were found to be present in A. hydrophila, of which one of them was indiscriminant towards a series of iron-siderophore complexes and iron complexes of siderophore analogs. The Fe(III) uptake proceeds via a redox-free ligand exchange mechanism in which iron from an iron-siderophore complex exchanges with a receptor-bound apo-siderophore. This exchange process is believed to be proton driven and is triggered by a pH gradient inside the β-barrel of the receptor.

Duke Scholars

Published In

Chemtracts

ISSN

1431-9268

Publication Date

August 6, 2001

Volume

14

Issue

5

Start / End Page

258 / 265

Related Subject Headings

  • Organic Chemistry
 

Citation

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Dhungana, S., & Crumbliss, A. L. (2001). Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm. Chemtracts, 14(5), 258–265.
Dhungana, S., and A. L. Crumbliss. “Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm.” Chemtracts 14, no. 5 (August 6, 2001): 258–65.
Dhungana S, Crumbliss AL. Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm. Chemtracts. 2001 Aug 6;14(5):258–65.
Dhungana, S., and A. L. Crumbliss. “Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm.” Chemtracts, vol. 14, no. 5, Aug. 2001, pp. 258–65.
Dhungana S, Crumbliss AL. Microbial iron transport via a siderophore shuttle: A membrane ion transport paradigm. Chemtracts. 2001 Aug 6;14(5):258–265.

Published In

Chemtracts

ISSN

1431-9268

Publication Date

August 6, 2001

Volume

14

Issue

5

Start / End Page

258 / 265

Related Subject Headings

  • Organic Chemistry