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Subfunctionalization: How often does it occur? How long does it take?

Publication ,  Journal Article
Ward, R; Durrett, R
Published in: Theoretical population biology
September 2004

The mechanisms responsible for the preservation of duplicate genes have been debated for more than 70 years. Recently, Lynch and Force have proposed a new explanation: subfunctionalization--after duplication the two gene copies specialize to perform complementary functions. We investigate the probability that subfunctionalization occurs, the amount of time after duplication that it takes for the outcome to be resolved, and the relationship of these quantities to the population size and mutation rates.

Duke Scholars

Published In

Theoretical population biology

DOI

EISSN

1096-0325

ISSN

0040-5809

Publication Date

September 2004

Volume

66

Issue

2

Start / End Page

93 / 100

Related Subject Headings

  • Time Factors
  • Probability
  • Population Density
  • Mutation
  • Models, Genetic
  • Gene Duplication
  • Evolutionary Biology
  • 4901 Applied mathematics
  • 3104 Evolutionary biology
  • 3103 Ecology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ward, R., & Durrett, R. (2004). Subfunctionalization: How often does it occur? How long does it take? Theoretical Population Biology, 66(2), 93–100. https://doi.org/10.1016/j.tpb.2004.03.004
Ward, Rachel, and Richard Durrett. “Subfunctionalization: How often does it occur? How long does it take?Theoretical Population Biology 66, no. 2 (September 2004): 93–100. https://doi.org/10.1016/j.tpb.2004.03.004.
Ward R, Durrett R. Subfunctionalization: How often does it occur? How long does it take? Theoretical population biology. 2004 Sep;66(2):93–100.
Ward, Rachel, and Richard Durrett. “Subfunctionalization: How often does it occur? How long does it take?Theoretical Population Biology, vol. 66, no. 2, Sept. 2004, pp. 93–100. Epmc, doi:10.1016/j.tpb.2004.03.004.
Ward R, Durrett R. Subfunctionalization: How often does it occur? How long does it take? Theoretical population biology. 2004 Sep;66(2):93–100.
Journal cover image

Published In

Theoretical population biology

DOI

EISSN

1096-0325

ISSN

0040-5809

Publication Date

September 2004

Volume

66

Issue

2

Start / End Page

93 / 100

Related Subject Headings

  • Time Factors
  • Probability
  • Population Density
  • Mutation
  • Models, Genetic
  • Gene Duplication
  • Evolutionary Biology
  • 4901 Applied mathematics
  • 3104 Evolutionary biology
  • 3103 Ecology