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Long-term mortality in patients with pauses in ventricular electrical activity.

Publication ,  Journal Article
Saba, MM; Donahue, TP; Panotopoulos, PTH; Ibrahim, SS; Abi-Samra, FM
Published in: Pacing Clin Electrophysiol
November 2005

BACKGROUND: The long-term significance of ventricular pauses of > or =3.0 seconds observed on Holter monitor is unclear, as previously conducted retrospective studies have been poorly controlled. We compared the prognosis of patients with pauses > or =3.0 seconds on Holter monitor with a well-matched control group without such pauses. METHODS: Scanning the Holter database at Ochsner Clinic (n = 11,730; January 1998 to June 2003) for pauses > or =3.0 seconds identified 70 patients (pause group). Of those, 29 (37.1%) received a permanent pacemaker (PPM group) and 41 (62.9%) did not (No-PPM group). For each No-PPM patient, two patients without pauses (<2.0 seconds) exactly matched for age, sex, ejection fraction (EF), rhythm, and duration of follow-up were randomly chosen from the Holter database (control group, n = 82) and survival of the two groups was compared. RESULTS: Mean age was 72.5 +/- 15.0 years, mean EF was 52.2 +/- 12.7%, and 68.3% were men. Mean follow-up was 2.2 years (0.5-4.5 years). There was no difference in survival between the No-PPM and the control groups (82.9% vs 84.1%, P = NS). Compared with the PPM group, pauses in the No-PPM group were more commonly asymptomatic, nocturnal, and due to sinus pauses or atrial fibrillation (AF) with slow ventricular response. CONCLUSIONS: Pauses in ventricular electrical activity > or =3 seconds on Holter monitor due to sinus pauses or AF with slow ventricular response are not predictive of heightened mortality.

Duke Scholars

Published In

Pacing Clin Electrophysiol

DOI

ISSN

0147-8389

Publication Date

November 2005

Volume

28

Issue

11

Start / End Page

1203 / 1207

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Survival Rate
  • Survival Analysis
  • Risk Factors
  • Risk Assessment
  • Retrospective Studies
  • Prevalence
  • Male
  • Louisiana
  • Longitudinal Studies
 

Citation

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Saba, M. M., Donahue, T. P., Panotopoulos, P. T. H., Ibrahim, S. S., & Abi-Samra, F. M. (2005). Long-term mortality in patients with pauses in ventricular electrical activity. Pacing Clin Electrophysiol, 28(11), 1203–1207. https://doi.org/10.1111/j.1540-8159.2005.50189.x
Saba, Magdi M., Timothy P. Donahue, Panagiotis T. H. Panotopoulos, Salma S. Ibrahim, and Freddy M. Abi-Samra. “Long-term mortality in patients with pauses in ventricular electrical activity.Pacing Clin Electrophysiol 28, no. 11 (November 2005): 1203–7. https://doi.org/10.1111/j.1540-8159.2005.50189.x.
Saba MM, Donahue TP, Panotopoulos PTH, Ibrahim SS, Abi-Samra FM. Long-term mortality in patients with pauses in ventricular electrical activity. Pacing Clin Electrophysiol. 2005 Nov;28(11):1203–7.
Saba, Magdi M., et al. “Long-term mortality in patients with pauses in ventricular electrical activity.Pacing Clin Electrophysiol, vol. 28, no. 11, Nov. 2005, pp. 1203–07. Pubmed, doi:10.1111/j.1540-8159.2005.50189.x.
Saba MM, Donahue TP, Panotopoulos PTH, Ibrahim SS, Abi-Samra FM. Long-term mortality in patients with pauses in ventricular electrical activity. Pacing Clin Electrophysiol. 2005 Nov;28(11):1203–1207.
Journal cover image

Published In

Pacing Clin Electrophysiol

DOI

ISSN

0147-8389

Publication Date

November 2005

Volume

28

Issue

11

Start / End Page

1203 / 1207

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Survival Rate
  • Survival Analysis
  • Risk Factors
  • Risk Assessment
  • Retrospective Studies
  • Prevalence
  • Male
  • Louisiana
  • Longitudinal Studies