The nested dirichlet process
In multicenter studies, subjects in different centers may have different outcome distributions. This article is motivated by the problem of nonparametric modeling of these distributions, borrowing information across centers while also allowing centers to be clustered. Starting with a stick-breaking representation of the Dirichlet process (DP), we replace the random atoms with random probability measures drawn from a DP. This results in a nested DP prior, which can be placed on the collection of distributions for the different centers, with centers drawn from the same DP component automatically clustered together. Theoretical properties are discussed, and an efficient Markov chain Monte Carlo algorithm is developed for computation. The methods are illustrated using a simulation study and an application to quality of care in U.S. hospitals.
Duke Scholars
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- Statistics & Probability
- 4905 Statistics
- 3802 Econometrics
- 1603 Demography
- 1403 Econometrics
- 0104 Statistics
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 3802 Econometrics
- 1603 Demography
- 1403 Econometrics
- 0104 Statistics