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Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft.

Publication ,  Journal Article
Clevens, RA; Esclamado, R; Naficy, S
Published in: Laryngoscope
October 1995

This study quantitatively examines the effects of laryngotracheal stenting with and without mucosal grafting on chondrogenesis in a rabbit model. Vascularized auricular perichondrium was transferred to a cricothyroid membrane (CTM) defect in three groups of New Zealand white rabbits: group A, CTM defect alone; group B, CTM defect with endotracheal tube stent; and group C, CTM defect with a buccal mucosa graft (BMG) interposed between the stent and perichondrium. The rabbits were sacrificed at 7 weeks for histologic examination and determination of cartilage thickness by digitometry. Chondrogenesis was not significantly affected by stenting (n = 11; 0.719 mm +/- 0.203 mm) or by BMG (n = 12; 0.775 mm +/- 0.203 mm) as compared with controls (n = 14; 0.695 mm +/- 0.216 mm) (P value = not significant). Laryngotracheal stenting and BMG do not adversely influence chondrogenesis in airway reconstruction with vascularized perichondrium in the rabbit model. The application of these principles in human airway reconstruction is discussed.

Duke Scholars

Published In

Laryngoscope

DOI

ISSN

0023-852X

Publication Date

October 1995

Volume

105

Issue

10

Start / End Page

1043 / 1048

Location

United States

Related Subject Headings

  • Tracheal Stenosis
  • Trachea
  • Time Factors
  • Stents
  • Random Allocation
  • Rabbits
  • Otorhinolaryngology
  • Mouth Mucosa
  • Larynx
  • Laryngostenosis
 

Citation

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ICMJE
MLA
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Clevens, R. A., Esclamado, R., & Naficy, S. (1995). Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft. Laryngoscope, 105(10), 1043–1048. https://doi.org/10.1288/00005537-199510000-00006
Clevens, R. A., R. Esclamado, and S. Naficy. “Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft.Laryngoscope 105, no. 10 (October 1995): 1043–48. https://doi.org/10.1288/00005537-199510000-00006.
Clevens, R. A., et al. “Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft.Laryngoscope, vol. 105, no. 10, Oct. 1995, pp. 1043–48. Pubmed, doi:10.1288/00005537-199510000-00006.
Journal cover image

Published In

Laryngoscope

DOI

ISSN

0023-852X

Publication Date

October 1995

Volume

105

Issue

10

Start / End Page

1043 / 1048

Location

United States

Related Subject Headings

  • Tracheal Stenosis
  • Trachea
  • Time Factors
  • Stents
  • Random Allocation
  • Rabbits
  • Otorhinolaryngology
  • Mouth Mucosa
  • Larynx
  • Laryngostenosis