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Stepwise self-assembly of DNA tile lattices using dsDNA bridges.

Publication ,  Journal Article
Park, SH; Finkelstein, G; LaBean, TH
Published in: Journal of the American Chemical Society
January 2008

The simple helical motif of double-strand DNA (dsDNA) has typically been judged to be uninteresting for assembly in DNA-based nanotechnology applications. In this letter, we demonstrate construction of superstructures consisting of heterogeneous DNA motifs using dsDNA in conjunction with more complex, cross-tile building blocks. Incorporation of dsDNA bridges in stepwise assembly processes can be used for controlling length and directionality of superstructures and is analogous to the "reprogramming" of sticky-ends displayed on the DNA tiles. Two distinct self-assembled DNA lattices, fixed-size nanoarrays, and extended 2D crystals of nanotracks with nanobridges, are constructed and visualized by high-resolution, liquid-phase atomic force microscopy.

Duke Scholars

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

January 2008

Volume

130

Issue

1

Start / End Page

40 / 41

Related Subject Headings

  • Nucleic Acid Conformation
  • Nanotechnology
  • Nanostructures
  • Microscopy, Atomic Force
  • General Chemistry
  • DNA
  • Crystallization
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

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Park, S. H., Finkelstein, G., & LaBean, T. H. (2008). Stepwise self-assembly of DNA tile lattices using dsDNA bridges. Journal of the American Chemical Society, 130(1), 40–41. https://doi.org/10.1021/ja078122f
Park, Sung Ha, Gleb Finkelstein, and Thomas H. LaBean. “Stepwise self-assembly of DNA tile lattices using dsDNA bridges.Journal of the American Chemical Society 130, no. 1 (January 2008): 40–41. https://doi.org/10.1021/ja078122f.
Park SH, Finkelstein G, LaBean TH. Stepwise self-assembly of DNA tile lattices using dsDNA bridges. Journal of the American Chemical Society. 2008 Jan;130(1):40–1.
Park, Sung Ha, et al. “Stepwise self-assembly of DNA tile lattices using dsDNA bridges.Journal of the American Chemical Society, vol. 130, no. 1, Jan. 2008, pp. 40–41. Epmc, doi:10.1021/ja078122f.
Park SH, Finkelstein G, LaBean TH. Stepwise self-assembly of DNA tile lattices using dsDNA bridges. Journal of the American Chemical Society. 2008 Jan;130(1):40–41.
Journal cover image

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

January 2008

Volume

130

Issue

1

Start / End Page

40 / 41

Related Subject Headings

  • Nucleic Acid Conformation
  • Nanotechnology
  • Nanostructures
  • Microscopy, Atomic Force
  • General Chemistry
  • DNA
  • Crystallization
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences