The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis.
Publication
, Journal Article
Cobb, AJ; Frothingham, R
Published in: Vet Microbiol
June 1, 1999
The GroES antigen provokes a strong immune response in human beings with tuberculosis or leprosy. We cloned and sequenced the Mycobacterium avium and Mycobacterium paratuberculosis GroES genes. M. avium and M. paratuberculosis have identical GroES sequences which differ from other mycobacterial species. This supports the current formal designation of M. paratuberculosis as M. avium subsp. paratuberculosis. Immunodominant epitopes from Mycobacterium tuberculosis GroES are conserved in M. avium, but some Mycobacterium leprae epitopes are distinct. GroES is unlikely to be specific as a serologic or skin test reagent, but may be an appropriate component of a broad mycobacterial vaccine.
Duke Scholars
Published In
Vet Microbiol
DOI
ISSN
0378-1135
Publication Date
June 1, 1999
Volume
67
Issue
1
Start / End Page
31 / 35
Location
Netherlands
Related Subject Headings
- Veterinary Sciences
- Sequence Homology, Amino Acid
- Sequence Analysis, DNA
- Sequence Alignment
- Polymerase Chain Reaction
- Mycobacterium avium subsp. paratuberculosis
- Mycobacterium avium
- Molecular Sequence Data
- Humans
- DNA, Bacterial
Citation
APA
Chicago
ICMJE
MLA
NLM
Cobb, A. J., & Frothingham, R. (1999). The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. Vet Microbiol, 67(1), 31–35. https://doi.org/10.1016/s0378-1135(99)00019-x
Cobb, A. J., and R. Frothingham. “The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis.” Vet Microbiol 67, no. 1 (June 1, 1999): 31–35. https://doi.org/10.1016/s0378-1135(99)00019-x.
Cobb AJ, Frothingham R. The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. Vet Microbiol. 1999 Jun 1;67(1):31–5.
Cobb, A. J., and R. Frothingham. “The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis.” Vet Microbiol, vol. 67, no. 1, June 1999, pp. 31–35. Pubmed, doi:10.1016/s0378-1135(99)00019-x.
Cobb AJ, Frothingham R. The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. Vet Microbiol. 1999 Jun 1;67(1):31–35.
Published In
Vet Microbiol
DOI
ISSN
0378-1135
Publication Date
June 1, 1999
Volume
67
Issue
1
Start / End Page
31 / 35
Location
Netherlands
Related Subject Headings
- Veterinary Sciences
- Sequence Homology, Amino Acid
- Sequence Analysis, DNA
- Sequence Alignment
- Polymerase Chain Reaction
- Mycobacterium avium subsp. paratuberculosis
- Mycobacterium avium
- Molecular Sequence Data
- Humans
- DNA, Bacterial