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Comparative analysis of commercial assays for the detection and quantification of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in plasma from patients infected with HIV-1 subtype C.

Publication ,  Journal Article
Hoesley, CJ; Allen, SA; Raper, JL; Musonda, R; Niu, Y; Gao, F; Squires, KE; Aldrovandi, GM
Published in: Clin Infect Dis
August 1, 2002

The commercial assays commonly used to quantify plasma human immunodeficiency virus type 1 (HIV-1) RNA in clinical settings were designed to assess HIV-1 subtype B. We compared the performance of 4 commercial assays (Amplicor versions 1.0 and 1.5 [Roche]; Quantiplex [Chiron]; and NASBA HIV-1 RNA QT [Organon Teknika]) in detecting and quantifying HIV-1 RNA in plasma from HIV-infected persons from Zambia, an area where HIV-1 subtype C is predominant. Each assay detected plasma HIV-1 RNA, but they do not all measure statistically similar quantities of plasma HIV-1 RNA.

Duke Scholars

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

August 1, 2002

Volume

35

Issue

3

Start / End Page

323 / 325

Location

United States

Related Subject Headings

  • Viral Load
  • RNA, Viral
  • Microbiology
  • Male
  • Humans
  • HIV-1
  • HIV Infections
  • Female
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hoesley, C. J., Allen, S. A., Raper, J. L., Musonda, R., Niu, Y., Gao, F., … Aldrovandi, G. M. (2002). Comparative analysis of commercial assays for the detection and quantification of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in plasma from patients infected with HIV-1 subtype C. Clin Infect Dis, 35(3), 323–325. https://doi.org/10.1086/341490
Hoesley, Craig J., Susan A. Allen, James L. Raper, R. Musonda, Yafen Niu, Feng Gao, Kathleen E. Squires, and Grace M. Aldrovandi. “Comparative analysis of commercial assays for the detection and quantification of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in plasma from patients infected with HIV-1 subtype C.Clin Infect Dis 35, no. 3 (August 1, 2002): 323–25. https://doi.org/10.1086/341490.
Hoesley CJ, Allen SA, Raper JL, Musonda R, Niu Y, Gao F, Squires KE, Aldrovandi GM. Comparative analysis of commercial assays for the detection and quantification of Human Immunodeficiency Virus Type 1 (HIV-1) RNA in plasma from patients infected with HIV-1 subtype C. Clin Infect Dis. 2002 Aug 1;35(3):323–325.
Journal cover image

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

August 1, 2002

Volume

35

Issue

3

Start / End Page

323 / 325

Location

United States

Related Subject Headings

  • Viral Load
  • RNA, Viral
  • Microbiology
  • Male
  • Humans
  • HIV-1
  • HIV Infections
  • Female
  • 3202 Clinical sciences
  • 11 Medical and Health Sciences