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Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs.

Publication ,  Journal Article
Yang, C; Dash, BC; Simon, F; van der Groen, G; Pieniazek, D; Gao, F; Hahn, BH; Lal, RB
Published in: J Infect Dis
May 2000

Human immunodeficiency virus type 1 (HIV-1) infection of humans is the result of independent cross-species transmissions of simian immunodeficiency viruses (SIVcpz) from naturally infected chimpanzees (Pan troglodytes troglodytes) to man. To develop a polymerase chain reaction-based assay capable of detecting members of all major phylogenetic SIVcpz and HIV-1 lineages (groups M, N, and O), primer pairs in conserved pol and env regions were designed. Both primer sets amplified 99%) in amplifying viral sequences from plasma taken from patients infected with HIV-1 group M (n=226) and O (n=17) viruses.

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Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

May 2000

Volume

181

Issue

5

Start / End Page

1791 / 1795

Location

United States

Related Subject Headings

  • Simian immunodeficiency virus
  • Simian Immunodeficiency Virus
  • Phylogeny
  • Pan troglodytes
  • Microbiology
  • Humans
  • HIV-1
  • Genetic Variation
  • Genes, pol
  • Genes, env
 

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Yang, C., Dash, B. C., Simon, F., van der Groen, G., Pieniazek, D., Gao, F., … Lal, R. B. (2000). Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs. J Infect Dis, 181(5), 1791–1795. https://doi.org/10.1086/315439
Yang, C., B. C. Dash, F. Simon, G. van der Groen, D. Pieniazek, F. Gao, B. H. Hahn, and R. B. Lal. “Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs.J Infect Dis 181, no. 5 (May 2000): 1791–95. https://doi.org/10.1086/315439.
Yang C, Dash BC, Simon F, van der Groen G, Pieniazek D, Gao F, Hahn BH, Lal RB. Detection of diverse variants of human immunodeficiency virus-1 groups M, N, and O and simian immunodeficiency viruses from chimpanzees by using generic pol and env primer pairs. J Infect Dis. 2000 May;181(5):1791–1795.
Journal cover image

Published In

J Infect Dis

DOI

ISSN

0022-1899

Publication Date

May 2000

Volume

181

Issue

5

Start / End Page

1791 / 1795

Location

United States

Related Subject Headings

  • Simian immunodeficiency virus
  • Simian Immunodeficiency Virus
  • Phylogeny
  • Pan troglodytes
  • Microbiology
  • Humans
  • HIV-1
  • Genetic Variation
  • Genes, pol
  • Genes, env