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Transforming the practice of medicine using genomics.

Publication ,  Journal Article
Ginsburg, GS; J McCarthy, J
Published in: Clin Cases Miner Bone Metab
January 2009

Recent studies have demonstrated the use of genomic data, particularly gene expression signatures, as clinical prognostic factors in complex diseases. Such studies herald the future for genomic medicine and the opportunity for personalized prognosis in a variety of clinical contexts that utilize genomescale molecular information. Several key areas represent logical and critical next steps in the use of complex genomic profiling data towards the goal of personalized medicine. First, analyses should be geared toward the development of molecular profiles that predict future events - such as major clinical events or the response, resistance, or adverse reaction to therapy. Secondly, these must move into actual clinical practice by forming the basis for the next generation of clinical trials that will employ these methodologies to stratify patients. Lastly, there remain formidable challenges is in the translation of genomic technologies into clinical medicine that will need to be addressed: professional and public education, health outcomes research, reimbursement, regulatory oversight and privacy protection.

Duke Scholars

Published In

Clin Cases Miner Bone Metab

ISSN

1724-8914

Publication Date

January 2009

Volume

6

Issue

1

Start / End Page

25 / 28

Location

Italy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ginsburg, G. S., & J McCarthy, J. (2009). Transforming the practice of medicine using genomics. Clin Cases Miner Bone Metab, 6(1), 25–28.
Ginsburg, Geoffrey S., and Jeanette J McCarthy. “Transforming the practice of medicine using genomics.Clin Cases Miner Bone Metab 6, no. 1 (January 2009): 25–28.
Ginsburg GS, J McCarthy J. Transforming the practice of medicine using genomics. Clin Cases Miner Bone Metab. 2009 Jan;6(1):25–8.
Ginsburg, Geoffrey S., and Jeanette J McCarthy. “Transforming the practice of medicine using genomics.Clin Cases Miner Bone Metab, vol. 6, no. 1, Jan. 2009, pp. 25–28.
Ginsburg GS, J McCarthy J. Transforming the practice of medicine using genomics. Clin Cases Miner Bone Metab. 2009 Jan;6(1):25–28.

Published In

Clin Cases Miner Bone Metab

ISSN

1724-8914

Publication Date

January 2009

Volume

6

Issue

1

Start / End Page

25 / 28

Location

Italy