The use of prophylactic eye drops during high-dose cytosine arabinoside therapy.
Publication
, Journal Article
Higa, GM; Gockerman, JP; Hunt, AL; Jones, MR; Horne, BJ
Published in: Cancer
October 15, 1991
An ocular toxic reaction presenting as conjunctivitis or keratitis develops in a significant number of patients who are treated with high-dose cytosine arabinoside (ara-C). Although eye drops containing glucocorticoid reportedly decrease the incidence, they do not totally eliminate this side effect. In comparing this technique with artificial tears, both were found to be equally effective. The primary mechanism by which eye drops decrease ocular toxic reactions associated with high-dose ara-C is presumably due to dilution of intraocular concentrations of ara-C.
Duke Scholars
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Published In
Cancer
DOI
ISSN
0008-543X
Publication Date
October 15, 1991
Volume
68
Issue
8
Start / End Page
1691 / 1693
Location
United States
Related Subject Headings
- Prednisolone
- Ophthalmic Solutions
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Leukemia, Myeloid, Acute
- Keratitis
- Humans
- Female
- Double-Blind Method
Citation
APA
Chicago
ICMJE
MLA
NLM
Higa, G. M., Gockerman, J. P., Hunt, A. L., Jones, M. R., & Horne, B. J. (1991). The use of prophylactic eye drops during high-dose cytosine arabinoside therapy. Cancer, 68(8), 1691–1693. https://doi.org/10.1002/1097-0142(19911015)68:8<1691::aid-cncr2820680805>3.0.co;2-w
Higa, G. M., J. P. Gockerman, A. L. Hunt, M. R. Jones, and B. J. Horne. “The use of prophylactic eye drops during high-dose cytosine arabinoside therapy.” Cancer 68, no. 8 (October 15, 1991): 1691–93. https://doi.org/10.1002/1097-0142(19911015)68:8<1691::aid-cncr2820680805>3.0.co;2-w.
Higa GM, Gockerman JP, Hunt AL, Jones MR, Horne BJ. The use of prophylactic eye drops during high-dose cytosine arabinoside therapy. Cancer. 1991 Oct 15;68(8):1691–3.
Higa, G. M., et al. “The use of prophylactic eye drops during high-dose cytosine arabinoside therapy.” Cancer, vol. 68, no. 8, Oct. 1991, pp. 1691–93. Pubmed, doi:10.1002/1097-0142(19911015)68:8<1691::aid-cncr2820680805>3.0.co;2-w.
Higa GM, Gockerman JP, Hunt AL, Jones MR, Horne BJ. The use of prophylactic eye drops during high-dose cytosine arabinoside therapy. Cancer. 1991 Oct 15;68(8):1691–1693.
Published In
Cancer
DOI
ISSN
0008-543X
Publication Date
October 15, 1991
Volume
68
Issue
8
Start / End Page
1691 / 1693
Location
United States
Related Subject Headings
- Prednisolone
- Ophthalmic Solutions
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Leukemia, Myeloid, Acute
- Keratitis
- Humans
- Female
- Double-Blind Method